Bulletin de veille Perturbateurs endocriniens, n°35, avril 2026
Exposition professionnelle
Pesticides associated with incident diabetes among licensed private pesticide applicators in the Agricultural Health Study cohort (1993-2021).
Parks CG, Xiao Q, Wilkerson J, Hofmann JN, Beane Freeman LE, Sandler DP. Environ Int. 2026 Feb;208:110082.
Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic-pituitary-gonadal axis.
Nita TM, Wrobel SA, Vernez D, Koch HM, Wild P, Zufferey F, et al. Environ Res. 2026 Feb 15;291:123477.
Occupational Exposure to Resorcinol and Thyroid-Disrupting Effects: Protocol for an Exploratory Field Study in French Hairdressers.
Radauceanu A, Cambrai-Erb A, Adet B, Nioule MI, Denis F, Pons R. JMIR Res Protoc. 2026 Mar 31;15:e65833.
Occupational exposure to endocrine-disrupting chemicals and colorectal cancer risk - An analysis of four participating cohorts of the Canadian Partnership for Tomorrow's Health study.
Pelland-St-Pierre L, Siemiatycki J, Dummer T, King WD, Koushik A, Lavoué J, et al. Environ Res. 2026 Mar 18;299:124299.
Indirect exposure to organophosphate pesticides and its possible growth disorders in children of farmers in Northwest Mexico.
Ochoa-Ruiz E, Moreno-García AI, Licea-Espinoza DA, Pineda-García G, Carranza-Ambriz KP, Soto-Rodriguez KK, et al. Int Arch Occup Environ Health. 2026 Jan 27;99(2):11.
Breast cancer-related occupational exposures facing immigrant women.
Knox KE, Ohayon JL, Carrera E, Rudel RA, Morello-Frosch R. J Expo Sci Environ Epidemiol. 2026 Mar;36(2):355-60.
Prenatal occupational exposure to endocrine-disrupting chemicals during pregnancy and adult male reproductive hormones.
Blanc-Petitjean P, Rahban R, Dananché B, Senn A, Zufferey F, Stettler E, et al. Reprod Biomed Online. 2026 Mar;52(3):105236.
Prenatal exposure to pesticides and the risk of male genital malformations: A scoping review,
Ariza, M., Lakehal, N., Fiani, M., Chardon, K. and Haraux, E., Reproductive Toxicology, Aug 2026, Vol. 143.
https://doi.org/10.1016/j.reprotox.2026.109238
Hidden risks associated with occupational pesticide exposure in women with breast cancer: High frequency of the Luminal B molecular subtype and occurrence of poor prognostic features,
Cazagranda, I. C., De Almeida, R. F., Smaniotto, L. L., Berny, M. P. D., Coradi, C., Rech, D., Panis, C. and Silveira, G. F., Plos One, Feb 5 2026, Vol. 21, no. 2.
https://doi.org/10.1371/journal.pone.0339471
Effect of occupation on assisted reproduction outcomes in an oocyte donor model,
Lee, J. C., Thornburgh, S., Nagy, Z. P., Shapiro, D. B., Hipp, H. S. and Gaskins, A. J., Archives of Environmental & Occupational Health, Apr 21 2026, Vol. 81, no. 3-4, p. 95-104.
https://doi.org/10.1080/19338244.2026.2640098
Linking Pesticide Exposure to Gestational Diabetes: Current Knowledge and Future Directions,
Pagkaki, C., Tsikouras, P. and Halvatsiotis, P., Physiologia, Jan 5 2026, Vol. 6, no. 1.
https://doi.org/10.3390/physiologia6010004
Perfluorooctane sulfonate (PFOS) in follicular fluid and human granulosa cell dysfunction: a physiologically based toxicokinetic model translation of long-term low-level in vitro exposure data,
Tomanic, T., Nenadov, D. S., Pletikosic, S. R., Stanic, B., Obradovic, D., Lazovic, S. and Andric, N., Human Reproduction Open, 2026 2026, Vol. 2026, no. 2.
https://doi.org/10.1093/hropen/hoag029
The effect of occupational lead toxicity on testosterone secretion and the L-arginine nitric oxide pathway,
Tutkun, L., İritaş, S. B., Büyükşekerci, M., Türksoy, V. A., Özkan Vardar, D., Öztan, Ö., Deniz, S., Dedeoğlu, Z. and Tutkun, E., Toxicology and Industrial Health, 2026/04/10/ 2026, p. 7482337261441688.
https://doi.org/10.1177/07482337261441688
Occupational exposure to inhalational anesthetics and the risk of spontaneous abortion: a systematic review and meta-analysis,
Ying, T. and Yuanqing, W., Frontiers in Public Health, Apr 1 2026, Vol. 14.
https://doi.org/10.3389/fpubh.2026.1766912
Epidémiologie
Associations of perfluoroalkyl and polyfluoroalkyl substances with markers of glycaemic control, insulin secretion and sensitivity, and diabetes risk: a systematic review and meta-analyses,
Aldana, S. I., Yu, X., Yao, M. Z., Cohen, N., Markopoulou, E., Chowdhury, M., Midya, V., Eick, S. M., Trowbridge, J., Starling, A. P., Barupal, D., Walker, D. I., Chatzi, L., Setiawan, V. W., Walker, R. W., Colicino, E. and Valvi, D., Eclinicalmedicine, Feb 2026, Vol. 92.
https://doi.org/10.1016/j.eclinm.2025.103747
Impact of antenatal exposure to a mixture of endocrine disruptors on attentional and executive functions in children,
Barrea, C., Dufour, P., Pirard, C., Charlier, C., Brévers, F., Parent, A. S. and Rousselle, L., Journal of the Endocrine Society, Apr 2026, Vol. 10, no. 4.
https://doi.org/10.1210/jendso/bvag057
Prenatal exposure to 33 endocrine-disrupting chemicals and pubertal development at age 9 in Spain,
Beneito, A., Carrizosa, C., Alvarez, O., Sarzo, B., Llop, S., Esplugues, A., Grimalt, J. O., Schettgen, T., Sakhi, A. K., Murcia, M., Freire, C., Ballester, F. and Lopez-Espinosa, M.-J., Environmental Research, 2026/07/01/ 2026, Vol. 301, p. 124527.
https://doi.org/10.1016/j.envres.2026.124527
Associations of prenatal exposure to bisphenols and phthalates with the fetoplacental ratio in the New York University Children's Health and Environment Study (NYU CHES),
Bommireddipalli, A., Erler, J. A., Nguyen, D. Q., Hyman, S., Spring, E., Medley, E. A., Kannan, K., Mehta-Lee, S. S., Trasande, L., Cowell, W. and Kahn, L. G., Ecotoxicology and Environmental Safety, Mar 1 2026, Vol. 312.
https://doi.org/10.1016/j.ecoenv.2026.119925
Per- and polyfluoroalkyl substances and adolescent bone mineral density: assessing periods of susceptibility,
Buckley, J. P., Marquess, K. M., Braun, J. M., Calafat, A. M., Cecil, K. M., Chen, A., Lanphear, B. P., Wasserman, H., Xu, Y., Yolton, K. and Kuiper, J. R., Journal of the Endocrine Society, 2026/04/01/ 2026, Vol. 10, no. 4, p. bvag039.
https://doi.org/10.1210/jendso/bvag039
Association between prenatal exposure to per- and polyfluoroalkyl substances and pubertal development in boys and girls in the Spanish INMA cohort,
Calle, S. L. D., Lertxundi, A., Alvarez, O., Lopez-Espinosa, M. J., Freire, C., Guxens, M., Schettgen, T., Le Bizec, B., Antignac, J. P., Vrijheid, M., Palacios, E. M., Cano-Sancho, G. and Irizar, A., Environmental Research, May 15 2026, Vol. 297.
https://doi.org/10.1016/j.envres.2026.124095
Elevated phthalate exposure and metabolic susceptibility increased breast cancer risk: A 20-y follow-up study in Taiwan,
Chen, H.-C., You, S.-L., Lin, C.-H., Sun, C.-W., Chiang, C.-J., Yang, H.-I., Wang, L.-Y., Sun, C.-A., Liu, J., Jen, C.-L., Chen, Y.-A., Lu, Y.-S., Cheng, A.-L., Wang, S.-L., Hsiung, C. A. and Chen, C.-J., Proceedings of the National Academy of Sciences, 2026/03/17/ 2026, Vol. 123, no. 11, p. e2507008123.
https://doi.org/10.1073/pnas.2507008123
Phthalates as the silent saboteurs of male fertility via changes in semen quality: a systematic review,
Dhar, S., Tomar, A., Anupama, N., Chatterjee, P. and Chatterjee, P. K., Reproductive Biology and Endocrinology, Mar 9 2026, Vol. 24, no. 1.
https://doi.org/10.1186/s12958-026-01541-0
Age at menarche and exposure to non-persistent pesticides in Spanish girls from the INMA (environment and childhood) project,
Freire, C., Olivas-Martinez, A., Castiello, F., Jimeno-Romero, A., Calle, S. L. D., Suárez, B., Tardón, A., Rodriguez-Suarez, M. M., Guxens, M., Vrijheid, M., Beneito, A. and Lopez-Espinosa, M. J., Environmental Research, Jun 15 2026, Vol. 300.
https://doi.org/10.1016/j.envres.2026.124450
Pregnancy exposure to environmental phenols and breastfeeding duration in the HOME Study,
Gerili, Z., Braun, J. M., Yolton, K., Lanphear, B., Romano, M. E., Tolstrup, J. and Timmermann, A., International Journal of Hygiene and Environmental Health, May 2026, Vol. 274.
https://doi.org/10.1016/j.ijheh.2026.114794
Per- and polyfluoroalkyl substances (PFAS) and miscarriage: The Norwegian Mother, Father and Child Cohort study,
Grindstad, T., Magnus, M. C., Di Nallo, A., Ramlau-Hansen, C. H., Liew, Z., Hanevik, H. I., Haug, L. S., Andersen, G. D., Rogne, T., Magnus, P., Papadopoulou, E., Håberg, S. E. and Caspersen, I. H., Environmental Research, Jun 1 2026, Vol. 298.
https://doi.org/10.1016/j.envres.2026.124276
Sex-specific associations of prenatal and postnatal exposure to 15 endocrine-disrupting chemical exposures with visual impairment at age three: the Korean Children's Environmental Health Study (Ko-CHENS),
Ham, D., Kim, S. Y., Bae, S. and Ko, C. S. G., Environment International, Apr 2026, Vol. 210.
https://doi.org/10.1016/j.envint.2026.110194
Associations of urinary and follicular fluid phthalate exposure with salpingitis in women seeking fertility treatment,
Hou, Q. Q., Liao, H. M., Zhang, Z. M., Yuan, J. Y., Guo, Q. C., Wang, Y., Li, J., Du, Y. Y., Zeng, Q., Deng, T. R. and Li, Y. F., Environmental Pollution, Jun 1 2026, Vol. 398.
https://doi.org/10.1016/j.envpol.2026.128057
Preterm birth attributable to exposure to chemicals used in plastic materials: a global estimate,
Hyman, S., Acevedo, J. and Trasande, L., eClinicalMedicine, 2026/04/01/ 2026, Vol. 94.
https://doi.org/10.1016/j.eclinm.2026.103842
Exploring the hidden cause of assisted reproductive technologies unfavorable outcomes through the biomonitoring study of heavy metals exposure among women,
Ilincic, M., Milosevic, N., Milanovic, M., Sazdanic-Velikic, D., Spanovic, M., Bjelica, A. and Milic, N., Journal of Trace Elements in Medicine and Biology, Jun 2026, Vol. 95.
https://doi.org/10.1016/j.jtemb.2026.127858
Age-Specific Association Between Urinary Phthalate Metabolites and Diabetes Mellitus: Findings from the Korean National Environmental Health Survey Cycle 4 (2018-2020),
Lee, J. E., Lee, G. T. and Cho, H. A., Healthcare, Mar 5 2026, Vol. 14, no. 5.
https://doi.org/10.3390/healthcare14050655
Exposure to phthalate and phenol mixtures and obesity in children and adolescents: the dominant role of bisphenol A,
Liu, F. Q., Li, Y., Kong, B. X., Liang, C. H., Chen, L., Xiong, J. F., Zhao, X., Su, Z., Xiao, P., Mi, J., Yao, P., Tang, Y. H. and Li, Y. Y., Lipids in Health and Disease, Mar 17 2026, Vol. 25, no. 1.
https://doi.org/10.1186/s12944-026-02903-8
The association between PFAS exposure, menstrual cycle parameters, and reproductive hormones in adolescent girls,
Malave-Ortiz, S., Mcneley, S. a. M., Denslow, S., Bangma, J., Ferguson, K. K., Fenton, S. E. and Shaw, N. D., Journal of Clinical Endocrinology & Metabolism, 2026.
https://doi.org/10.1210/clinem/dgag148
Exposure to organophosphate esters and trajectories of gestational weight gain: A large prospective cohort study,
Martin, B., Cantonwine, D. E., Meeker, J. D., Ospina, M., Calafat, A. M., Mcelrath, T. F., Ferguson, K. K. and Welch, B. M., Environmental Research, Jun 15 2026, Vol. 300.
https://doi.org/10.1016/j.envres.2026.124434
Associations of Urinary Metabolites of Parabens and Bisphenol a with Premature Thelarche among a Sample of Iranian Girls,
Mozafarian, N., Hashemipour, M., Maracy, M. R., Galehdari, H. and Kelishadi, R., Journal of Clinical Research in Pediatric Endocrinology, Mar 2026, Vol. 18, no. 1, p. 85-96.
https://doi.org/10.4274/jcrpe.galenos.2025.2025-3-22
Exposure to Obesogenic Endocrine Disruptors in Childhood. Impact on Biomarkers of Metabolic Status,
Nso-Roca, A. P., Tortajada-Genaro, L. A., Pons-Fernández, N. and Sánchez-Ferrer, F., Exposure and Health, Mar 18 2026, Vol. 18, no. 2.
https://doi.org/10.1007/s12403-026-00764-1
Association of exposure to synthetic phenols and metal(loid)s with early puberty in Spanish girls: a multicentric case-control study,
Olivas-Martinez, A., Escribano, A., Riaño-Galán, I., Torrebias, M., Olmedo, P., Gil, F., Suarez, B., Rodríguez-Carrillo, A., Corripio, R., Castiello, F., Bosch, M. Z., Herrero, X., Ventura-Wichner, P. S. and Freire, C., European Journal of Pediatrics, Apr 24 2026, Vol. 185, no. 5.
https://doi.org/10.1007/s00431-026-06919-1
Per- and Polyfluoroalkyl Substances and Endometriosis: A Systematic Review and Meta-Analysis,
Pilling, S., Mitchell, K. and Ramdass, P. V. a. K., Toxics, 2026/04// 2026, Vol. 14, no. 4, p. 337.
https://doi.org/10.3390/toxics14040337
A prospective study of per- and polyfluoroalkyl substances (PFAS), stress, and birth size in a cohort of US Black women,
Schildroth, S., Henn, B. C., Lovett, S. M., Wesselink, A. K., Nillni, Y. I., Heiger-Bernays, W., Harmon, Q. E., Vines, A. I., Baird, D. D. and Wise, L. A., Environmental Health, Feb 27 2026, Vol. 25, no. 1.
https://doi.org/10.1186/s12940-026-01279-7
Joint effects of prenatal endocrine disrupting chemicals and heavy metal mixture on birth size and maternal complication in the Korea children's environmental health cohort study,
Shim, S. R., Moon, N. and Kim, J. H., Environmental Research, Jun 15 2026, Vol. 299.
https://doi.org/10.1016/j.envres.2026.124368
Exposure to Endocrine Disruptors and Stress Hormones Across Pregnancy Trimesters: Links with Maternal Telomere Length,
Vakonaki, E., Hatzidaki, E., Baliou, S., Marmara, M., Alegakis, A., Mylonaki, E., Volonaki, Z., Makrygiannakis, F., Tsatsakis, A. and Tzatzarakis, M. N., Journal of Xenobiotics, 2026/06// 2026, Vol. 16, no. 3, p. 82.
https://doi.org/10.3390/jox16030082
Fetal exposure to bisphenols and phthalates and risk of respiratory conditions in infancy. The Generation R Next Study,
Varma, P., Karramass, T., Trasande, L., Ferguson, K. K., Kannan, K., Sakhi, A. K., Jaddoe, V. W. V. and Duijts, L., Environmental Research, Jun 15 2026, Vol. 299.
https://doi.org/10.1016/j.envres.2026.124304
Preliminary Evidence of Microplastics in the Human Thyroid and Their Potential Association with Autoimmune Thyroiditis,
Yu, S. T., Fu, J. R., Fan, Z. H., Ye, Q. T., Zhang, S. L. and Guan, H. X., Thyroid, 2026.
https://doi.org/10.1177/10507256261442506
Toxicité sur l’homme
Urinary non-persistent environmental chemicals in pregnancy: Associations with subclinical renal injury and exposure determinants,
Chen, C. C., Wang, Y. H., Wu, C. F., Hsieh, C. J., Wang, S. L., Chen, M. L., Tsai, H. J., Li, S. S., Cheng, C. M. and Wu, M. T., Journal of Hazardous Materials Advances, May 2026, Vol. 22.
exposure mitigation strategies to protect maternal renal health. https://doi.org/10.1016/j.hazadv.2026.101153
Endocrine-disrupting properties of heavy metal exposure contribute to the intergenerational effects on learning and memory,
Dias, G. R. M., Zomer, H. D., Silva, N. F. and Graceli, J. B., Frontiers in Endocrinology, Mar 26 2026, Vol. 17.
https://doi.org/10.3389/fendo.2026.1761556
Integrative computational and experimental analysis identifies MEK-mediated carcinogenic effects of bisphenol A and diethyl phthalate in head and neck cancer,
Ding, R., Quan, T. Q., Wu, J. X., Huang, R., Liang, L. D., Quan, Q. and Long, Z. Q., Ecotoxicology and Environmental Safety, Mar 1 2026, Vol. 312.
. https://doi.org/10.1016/j.ecoenv.2026.119924
The contribution of phenolic endocrine-disrupting chemicals to breast cancer risk: A comprehensive bioinformatics analysis,
Dou, Y. H., Li, X. X., Li, M., Shang, J. and Xu, T., Scientific Reports, Feb 11 2026, Vol. 16, no. 1.
https://doi.org/10.1038/s41598-026-39706-x
Impact of PFAS exposure on lipid metabolic pathways: mechanisms and implicatins in carcinogenesis,
Ferguson, E. J., Tessmann, J. W. and Zaytseva, Y. Y., Frontiers in Toxicology, Mar 11 2026, Vol. 8.
https://doi.org/10.3389/ftox.2026.1768277
Exposure to per- and polyfluoroalkyl substances (PFAS) and development of autoimmunity in humans and animals: a scoping review,
Holm-Larsen, C. E., Siggaard, L. W. L., Sander, S. D., Ostengaard, L. and Husby, S., Archives of Toxicology, 2026.
https://doi.org/10.1007/s00204-026-04381-4
Benzalkonium chloride and its derivatives as 5α-reductase 1 inhibitors to disrupt neurosteroid biosynthesis,
Huang, Y., Ding, C., Wang, S., Qi, S., Zhu, H., Wang, Y., Ge, R.-S., Liu, Y. and Cheng, J., Bioorganic Chemistry, 2026/07/15/ 2026, Vol. 176, p. 109850.
https://doi.org/10.1016/j.bioorg.2026.109850
Unraveling the endocrine disruption potential of microplastics in testosterone regulation,
Khawar, M. B., Afzal, A., Jalil, K., Jan, T. Y. Y., Ahmad, Z., Rehman, A., Afzal, H., Ahmad, S., Nimra, A. and Ashraf, M. A., Journal of Environmental Sciences, Jun 2026, Vol. 164, p. 827-836.
https://doi.org/10.1016/j.jes.2025.12.063
Overloaded mitochondrial stress drives reproductive damage in GC-1 mouse spermatogonia cells exposed to nickel nanoparticle,
Kong, L., Liang, G. Y. and Wang, Y., Cell Biology and Toxicology, Feb 11 2026, Vol. 42, no. 1.
https://doi.org/10.1007/s10565-026-10153-8
An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro,
Land, K. L., Xu, H., Akin, J. W. and Hannon, P. R., Environment International, Mar 2026, Vol. 209.
https://doi.org/10.1016/j.envint.2026.110183
Glycolytic metabolic reprogramming and mitochondrial dysfunction: A novel mechanism underlying PAEs-promoted cartilage inflammatory phenotype,
Liu, L., Chen, Y. C., Lin, W. Y., Zheng, M., Yu, T. Q., Chen, R. Y., Yang, Y. R., Jiao, L. L., Ruan, Q. L. and Sun, J., Ecotoxicology and Environmental Safety, Mar 15 2026, Vol. 313.
https://doi.org/10.1016/j.ecoenv.2026.120027
Bisphenol A and breast cancer: Can mechanistic plausibility be reconciled with epidemiological inconsistency?,
Liu, Y., Cao, H. L., Zhang, S. Y., Li, Q. H., Wang, X., Ma, M. Y., Zhou, Y. and Han, B., Iscience, Apr 17 2026, Vol. 29, no. 4.
https://doi.org/10.1016/j.isci.2026.115421
Persistent organic pollutants and prostate cancer: multiple mechanisms and comprehensive control strategies,
Lv, C. S., Cao, H. L., Li, S. X., Du, H., Yang, L. C., Wang, L. M., Liu, S. Y., Zhou, H. L. and Gao, J. L., Frontiers in Cell and Developmental Biology, Mar 11 2026, Vol. 14.
basis for formulating evidence-based, precise prevention and treatment strategies. https://doi.org/10.3389/fcell.2026.1741752
Endocrine disruptors are contributing to type 2 diabetes mellitus,
Magnifico, S., Hinault-Boyer, C. and Chevalier, N., Hormones-International Journal of Endocrinology and Metabolism, 2026.
https://doi.org/10.1007/s42000-026-00779-y
Bisphenol a and polycystic ovary syndrome in reproductive-age women: mechanistic exploration via network toxicology and molecular docking,
Peng, C. S., Wang, C. X., Chen, J. and Chen, H., Journal of Ovarian Research, Feb 28 2026, Vol. 19, no. 1.
https://doi.org/10.1186/s13048-026-02049-2
Dietary Microplastics Engage Gut Mechanosensory-Endocrine Signaling to Disrupt Bone Homeostasis,
Romero, A. S., Phatak, S., Patil, S., Dar, H. Y., Rivas, J. A., Oyebamiji, O. M., Maes, B. B., Goitom, S. S., Enriquez, C. M., Orozco, J., Coffman, C. N., Liu, R., In, J. G., Campen, M. J., Cook, K., Levenson, R., Gross, J. M., Leng, S., Cretara, A., Pacifici, R. and Castillo, E. F., bioRxiv, 2026/04/07/ 2026.
https://doi.org/10.64898/2026.04.03.716216
Synergistic toxicity of endocrine disruptors and environmental toxicants under climate change,
Seo, J., Jeong, M. and Ham, J., Molecular & Cellular Toxicology, 2026.
https://doi.org/10.1007/s13273-026-00617-7
Structural Insights into the Interaction of Bisphenol F (BPF) and Bisphenol S (BPS) with Estrogen Receptors for Endocrine Safety Assessment,
Sheikh, I. A., Bhat, I. U., Zughaibi, T. A., Ghorab, M. A., Rehan, M., Almutairi, M. F., Beg, M. A., Tariq, Z. and Kadry, A. R. M., Toxics, Mar 17 2026, Vol. 14, no. 3.
https://doi.org/10.3390/toxics14030262
Effects of bisphenol A and bisphenol S on human fallopian tube contractions: An in vitro and in silico study,
Singh, R., Sharma, P., Agarwal, S., Modanwal, S., Paulraj, S. and Mahto, S. K., Reproductive Toxicology, May 2026, Vol. 142.
https://doi.org/10.1016/j.reprotox.2026.109211
Mechanisms of reproductive toxicity and endocrine disruption of bisphenols and per-and polyfluoroalkyl substances (PFAS): Implications for women's reproductive health,
Stone, A. M., Fung, G. H., Joseph, A., Biernat, M. M., Camp, O. G. and Abu-Soud, H. M., Reproductive Toxicology, Aug 2026, Vol. 143.
https://doi.org/10.1016/j.reprotox.2026.109239
Decoding tamoxifen on idiopathic pulmonary fibrosis: integrating network toxicology and multi-omics,
Sun, Y. H., Lu, Z. Y., Yu, W. Y., Huang, S. Q., Xie, Y. X., Yao, D., Wang, H. W., Wu, Q., Huang, X. Y. and Li, X. C., International Journal of Surgery, Feb 2026, Vol. 112, no. 2, p. 2696-2716.
https://doi.org/10.1097/js9.0000000000003620
Insights to cellular and molecular impacts of micro/nanoplastics and their additives for carcinogenic risks,
Verma, S. K., Mishra, S., Simnani, F. Z., Sinha, A., Kaushik, A., Ghosh, A. and Mishra, Y. K., Results in Chemistry, Jul 5 2026, Vol. 26.
. https://doi.org/10.1016/j.rechem.2026.103297
Metals/Metalloids Profile in Seminal Plasma/Serum of Patients with Asthenozoospermia/Oligozoospermia: Correlation with Semen Quality,
Wang, Y., Zhao, S. Y., Liu, Y. N., Zhang, J. B., Cao, L. Q., Jiang, P. and Qiao, Y. Y., Biological Trace Element Research, 2026.
. https://doi.org/10.1007/s12011-026-05045-1
The Endocrine Disrupting Compounds Bisphenol-A and α-Zeranol Mimic the Estrogen Transcriptional Program to Promote Proliferation and Stemness in Breast Cancer Cells,
Winz, C., Li, E., Xie, C., Lee, K. C., Boguszewski, K., Rohatagi, S., Hahn, R., Rancourt, R., Furmanski, P. and Suh, N., Molecular Carcinogenesis, 2026/05/03/ 2026.
https://doi.org/10.1002/mc.70127
Endocrine Noise: Sex-Specific Disruption of Hypothalamic–Pituitary–Adrenal (HPA) Axis by Endocrine-Disrupting Chemicals,
Xega, V., Yang, M. H. and Liu, J.-L., Sexes, 2026/06// 2026, Vol. 7, no. 2, p. 22.
https://doi.org/10.3390/sexes7020022
Reproductive toxicity mechanisms of PNMC: Evidence from mitochondrial dysfunction and hormone synthesis disruption in the KGN cells,
Xie, J. Y., Pan, Z. X., Du, Y. H., Li, K. X., Liu, Y. N., Weng, Q. and Zhang, H. L., Reproductive Toxicology, May 2026, Vol. 142.
. https://doi.org/10.1016/j.reprotox.2026.109223
PFAS and adipokines: Decoding their roles in the risk of breast nodules and breast cancer,
Xu, M. Y., Zhu, X. Y., Liu, Y. Y., Liu, X. Z., Liu, W. L., Lin, B. H., Zheng, Y. Y., Liu, K., Feng, Y., Alhazmi, N., Ma, S. T., Chen, H., Bai, Y. S. and Wang, H. H., Environmental Research, Jun 1 2026, Vol. 298.
https://doi.org/10.1016/j.envres.2026.124293
Effects of Zearalenone on the Kiss1/GPR54 System and Related Genes Expression in the Hypothalamus and Pituitary Gland of Weaned Gilts,
Yuan, Z., Zhou, M., Luan, Y., Kong, L., Yang, W. and Jiang, S., Toxins, 2026/05// 2026, Vol. 18, no. 5, p. 195.
https://doi.org/10.3390/toxins18050195
The impact of Di(2-ethylhexyl) phthalate on human organ development: mechanisms and clinical relevance review,
Zhao, X., Hua, L., Xiong, Y., Shi, F., Zhong, Y., Zhang, S., Yu, D. and Tian, C., Frontiers in Public Health, 2026/05/04/ 2026, Vol. 14.
https://doi.org/10.3389/fpubh.2026.1830552
Network toxicology & molecular docking: endocrine-disrupting chemicals induce prostate cancer-a system study,
Zhou, Y., Zhou, G. M., Zhang, Y. J., Deng, C. H., Li, Z. S. and Hu, X. D., International Journal of Clinical and Experimental Pathology, 2026 2026, Vol. 19, no. 3, p. 116-129.
https://doi.org/10.62347/pgnw5316
Endocrine-disrupting chemicals and polycystic ovary syndrome: A systems toxicology perspective on mechanistic pathways,
Zhu, X. J., Xu, W. T. and Lu, A. F., Reproductive Toxicology, May 2026, Vol. 142.
https://doi.org/10.1016/j.reprotox.2026.109233
Méthodes
New Method to Sample and Determine 4-AP in the Workplace Air,
Dobrzynska, E. and Kowalska, J., Aerosol and Air Quality Research, Mar 25 2026, Vol. 26, no. 4.
. https://doi.org/10.1007/s44408-026-00107-4
Application of the click analytical chemistry index for the assessment of endocrine-disrupting chemicals in cosmetics and personal care products,
Fuente-Ballesteros, A., Jano, A., Custodio-Mendoza, J. A., Samanidou, V., Mansour, F. R., Ares, A. M. and Bernal, J., Journal of Chromatography A, 2026/07/05/ 2026, Vol. 1778, p. 466990.
https://doi.org/10.1016/j.chroma.2026.466990
Determining EDC exposure: direct analytical methods are essential for accurate analysis of human biospecimens,
Gerona, R., Sovereign, A., French, D., Gonzaga, M. J., Vom Saal, F. S. and Hunt, P., Journal of the Endocrine Society, May 2026, Vol. 10, no. 5.
. https://doi.org/10.1210/jendso/bvag076
Machine Learning Prediction of Transthyretin Binding for Thyroid Hormone Transport Disruption for Chemical Risk Assessment,
Hou, S. K., Ji, C., Reh, C. M. and Ruiz, P., Toxics, Mar 10 2026, Vol. 14, no. 3.
https://doi.org/10.3390/toxics14030240
Development of an in vitro method for simultaneous evaluation of androgenic activity of chemicals and their metabolites using S9: Application in biocides,
Kim, N. Y., Kwon, Y. K., Yang, E., Lee, G. and Lee, H. Y., Food and Chemical Toxicology, Jul 2026, Vol. 213.
https://doi.org/10.1016/j.fct.2026.116076
Screening of Estrogenic and Antiestrogenic Effects of Estradiol, Bisphenol A, and Fulvestrant Using 2D and 3D Breast Cancer Cell Systems With a Luciferase Reporter Gene Assay,
Monteleone, V., Barbaro, K., Elisa, I., Daniele, M., Bisegna, S., Mollari, M., Galli, F., Cittadini, M., Zepparoni, A., Caciolo, D., Sittinieri, S., Altigeri, A., Alimonti, C., Ciurli, G., Cimmino, A., Cortese, F., Sagrafoli, D., Villa, R., Zilli, R. and Scicluna, M., Journal of Applied Toxicology, 2026.
https://doi.org/10.1002/jat.70168
EDC Profiler: A High-Throughput Screening Server for Identifying Endocrine Disrupting Chemicals toward Multiple Nuclear Receptors,
Qiu, Y., Cui, S., Zhang, H., Huang, Y., Chen, X., Zhao, Y., Zhuang, S. and Jiang, G., Environmental Science & Technology, 2026/05/05/ 2026.
https://doi.org/10.1021/acs.est.5c18135
Agenda, actualité, politique
Derrière le scandale du cadmium, une surexposition globale aux contaminants chimiques,
Techniques de l'Ingénieur
Lithium : mieux connaître les expositions pour maîtriser les risques sanitaires et environnementaux
New online course: EDCs 101 - EHN.
https://environmental-health-sciences-2e3799.circle.so/c/ehs-training-program
SCCS Scientific advice on Butylated Hydroxyanisole (BHA) - Public Health.
European Commission
https://health.ec.europa.eu/publications/sccs-scientific-advice-butylated-hydroxyanisole-bha_en
Webinar. Prenatal Exposure to OP Pesticides: Health outcomes & potential mechanisms. May 19, 2026. 3 pm US Eastern Time,
Collaborative for Health & Environment.
https://www.healthandenvironment.org/che-webinars/97145
Chloroéthane : proposition de classement comme toxique pour la reproduction et perturbateur endocrinien.,
ANSES (28 avril 2026),
ECHA’s Socio-Economic Analysis Committee agrees its draft opinion on PFAS restriction proposal,
ECHA (11 mars 2026),
Voir aussi : https://echa.europa.eu/-/echa-supports-pfas-restriction-with-targeted-derogations https://echa.europa.eu/-/echa-s-socio-economic-analysis-committee-agrees-its-draft-opinion-on-pfas-restriction-proposal
Etendre le nombre de phtalates classés toxiques pour la reproduction et perturbateurs endocriniens dans le règlement CLP,
ANSES (2 mars 2026),
Le fluor dans les dentifrices est-il dangereux pour la santé ?
60 Millions de Consommateurs, 2026/04/13
Lithium : mieux connaître les expositions pour maîtriser les risques sanitaires et environnementaux,
ANSES (2026),
Perturbateurs endocriniens : le Gouvernement consulte sur ses priorités et son plan d'actions,
Actu-Environnement, 2026/04/13.
Perturbateurs endocriniens et médicaments : le mal est-il dans le remède ?
Le Moniteur des pharmacies (2026/04/30),
PFAS restriction: ECHA Committees’ opinions and next steps,
ECHA (7 mai 2026),
https://echa.europa.eu/-/pfas-2026-echa-committees-opinions
Podcast: How Do Endocrine Disruptors Impact Our Health? | Health Matters | NYP,
NewYork-Presbyterian, 2026/03/11.
https://www.nyp.org/healthmatters/podcast-how-do-endocrine-disruptors-impact-our-health
Replay Webinaire : Development and real-life application of adverse outcome pathways for endocrine disruption,
ECHA (14 avril 2026),
Vidéo - Metabolic endocrine disruptors: Methods for the identification of metabolism disrupting chemicals ECHA / Utrecht University (28 avril 2026),
https://www.youtube.com/watch?v=aZ9xKRoj79E
Webinaire : Des micro et nanoplastiques aux PFAS : recherches sur ces pollutions diffuses. jeudi 28 mai. 11h/12h30.,
ANSES (28 mai 2026),
https://ajspi.com/communiques-club/invitation-presse-4-webinaires-pour-feter-les-20-ans-du-pnr-est/
https://survey.anses.fr/SurveyServer/s/DFRV/polludiff/questionnaire.htm
Empowerment et rupture d'habitudes : une étude qualitative sur le changement de comportement vers des cosmétiques plus sains pour la santé,
Berenguel, G., Ojeda Trujillo, M.-B., Helme-Guizon, A., Louvel, S. and Philippat, C., (2026/05),
https://hal.science/hal-05608096
Impacts of environmental stressors on fertility and fecundity across taxa, with implications for planetary health,
Brander, S. M., Swan, S. H., Mehinto, A. C., Kidd, K. A., Weis, J. S., Belcher, S. M., Dewitt, J. C., Harper, S. L. and Helbing, C. C., npj Emerging Contaminants, 2026/04/23/ 2026, Vol. 2, no. 1, p. 12.
https://doi.org/10.1038/s44454-026-00032-6
Réduire son usage des cosmétiques permet de diminuer rapidement l’exposition à certains polluants chimiques et perturbateurs endocriniens comme le bisphénol A,
Cara, G., Salle de presse de l'Inserm (2026/04/22),
Epidemiological studies and disease burden assessment of emerging contaminants,
Cui, Y. D., Xu, T. B., Niu, Y., Chen, R. J., Ji, J. S. and Kan, H. D., Chinese Science Bulletin-Chinese, 2026 2026, Vol. 71, no. 12, p. 2587-2601.
https://doi.org/10.1360/csb-2025-0225
ONE HEALTH SUMMIT : Santé-environnement : la France change d'échelle avec une stratégie nationale fondée sur “Une seule santé”,
Dgs_Céline.M and Dgs_Céline.M, Ministère de la Santé, de la Famille, de l'Autonomie et des Personnes handicapées.
Cadmium : pourquoi les femmes sont plus exposées,
Hiver, L., Vert (2026/04/09),
https://vert.eco/articles/cadmium-pourquoi-les-femmes-sont-plus-exposees
Réglementation européenne et actions administratives françaises face aux perturbateurs endocriniens : vers une harmonisation des critères d’identification pour une prise en compte efficace au niveau national,
Michel-Caillet, C., Environnement, Risques & Santé, 2026/03/01, Vol. 25, no. 2, p. 123-130.
https://doi.org/10.1684/ers.2026.1918
"If They Are Not Labeled, How Do We Know What's Risky and What's Not?": Assessing Information on Brominated Flame Retardants in Children's Plastic Products in South Africa,
Mlelwa, R. and Rother, H. A., Environmental Health Insights, 2026 Vol. 20.
https://doi.org/10.1177/11786302261435748
Projet de priorités d’actions de l’Etat et de plan d’actions sur les perturbateurs endocriniens,
Publiques, C., Consultations publiques, 2026/04/10.
Research priorities for the adverse health effects of emerging contaminants,
Tang, S., Lyu, Y. B., Wang, Q., Duan, L. N., Gu, W., Xu, Y. J., Yang, X. Y., Lu, Y. F., Shen, H. B. and Shi, X. M., Chinese Science Bulletin-Chinese, 2026 2026, Vol. 71, no. 12, p. 2571-2586.
https://doi.org/10.1360/csb-2025-0307
Evaluation de l’exposition
Endocrine-disrupting chemicals in breast milk and early life exposure for infants in the United States,
Hazlehurst, M. F., Liu, C., Zheng, G., Koch, M., Schreder, E., Salamova, A. and Sathyanarayana, S., Journal of Exposure Science & Environmental Epidemiology, 2026/05// 2026, Vol. 36, no. 3, p. 550-558.
https://doi.org/10.1038/s41370-026-00844-z
Targeting Plastic Exposure in Infertile Couples: A Pilot Intervention Study,
Hua, J. N., Rochester, J. R., Foley, J. M., Hahn, L. B., Min, M. Y., Kenfield, S. A., Smith, J. F. and Swan, S. H., Toxics, Mar 16 2026, Vol. 14, no. 3.
https://doi.org/10.3390/toxics14030257
Mixture risk assessment of nine reproductive toxic chemicals affecting male sperm quality in a representative sample of children and adolescents living in Germany - results from the German Environmental Survey (GerES V),
Koelman, L., Lange, R., Kolossa-Gehring, M. and Murawski, A., International Journal of Hygiene and Environmental Health, May 2026, Vol. 274.
https://doi.org/10.1016/j.ijheh.2026.114783
Identification and Characterization of Key Hazardous Substances in Precocious Puberty Children: An Internal Exposure Assessment in China's Typical Coastal Cities,
Li, X., Zhang, H., Zhao, X. Q., Ren, F., Jin, J., Peng, Y. H., Guo, C. C., Dai, Y. B., Cao, R., Geng, N. B., Chen, J. P. and Wu, L. D., Environment & Health, 2026.
https://doi.org/10.1021/envhealth.5c00693
Sociodemographic and Lifestyle Factors Associated with Historical Exposure to Persistent Flame Retardant Concentrations in a Spanish Cohort,
Linares-Ruiz, E., Pérez-Díaz, C., Pérez-Carrascosa, F. M., Gonzalez, S., Ramos, J. J., Salcedo-Bellido, I. and Arrebola, J. P., Applied Sciences-Basel, Feb 28 2026, Vol. 16, no. 5.
https://doi.org/10.3390/app16052346
Toxicité sur les animaux
Investigating ovarian effects of perfluorooctanoic acid in postpubertal pigs during thermal neutral and heat stress conditions,
Antwi-Boasiako, C., González-Alvarez, M. E., Buol, B. M., Adeyanju, O., Baumgard, L. H. and Keating, A. F., Journal of Animal Science, 2026 2026, Vol. 104.
https://doi.org/10.1093/jas/skag062
Sex-specific disruption of estrogen receptor alpha (ERα) density in the social brain neural network by Firemaster 550,
Cao, J., Gillera, S. E. A., Marinello, W. P. and Patisaul, H. B., Journal of the Endocrine Society, 2026/04// 2026, Vol. 10, no. 4, p. bvag050.
https://doi.org/10.1210/jendso/bvag050
The effects of desflurane on male rat reproductive hormones, testicular tissue, and sperm morphology: an experimental study,
Dogru, S., Dogru, H. Y., Tapar, H., Arici, A. and Suren, M., Bmc Anesthesiology, Feb 6 2026, Vol. 26, no. 1.
https://doi.org/10.1186/s12871-026-03668-4
Endocrine and metabolism modulating effects of paracetamol: From in vitro signaling to in vivo metabolic reprogramming in male mice,
Entezari, B., Bozdag, D., Buhur, A., Sabuncuoglu, S., Yavasoglu, A. and Gurer-Orhan, H., Toxicology, Aug 2026, Vol. 524.
Effects of Maternal Tetramethyl Bisphenol F Exposure on Neurodevelopment and Behavior in Mouse Offspring,
Hwang, I., Kim, S. and Jeung, E. B., International Journal of Molecular Sciences, Apr 5 2026, Vol. 27, no. 7
https://doi.org/10.3390/ijms27073299
Diethyl phthalate-induced oxidative stress, genotoxicity, and thyroid hormone disruption in female Wistar rats,
Kömürcü, A. and Yavas, M. C., Food and Chemical Toxicology, Jun 2026, Vol. 212.
https://doi.org/10.1016/j.fct.2026.116031
Maternal Bisphenol S Exposure Impairs Testicular Development and Sperm Function in Male Offspring by Disrupting the Immune-Endocrine Network,
Li, B., Tian, Y., Wu, X., Gong, Z., Liang, X., Zhang, J., Hu, Y., Ji, X. and Yue, H., Small, Vol. n/a, no. n/a, p. e13075.
experimental evidence of the reproductive toxicity of environmentally relevant BPS in male offspring. https://doi.org/10.1002/smll.202513075
Maternal exposure to phthalates and nanoplastics, isolated or combined: Impacts on placental structure, development, and antioxidant defense as a trigger for maternal-fetal adversities,
Magosso, N., Souza, P. V., Moreira, M. F., Rocha, V. A., Fioretto, M. N., Pinha, V. C., Maia, G. A., Maria, V., Barata, L. A., Frigoli, G. F., Fernandes, G. S. A., Arena, A. C. and Scarano, W. R., Reproductive Toxicology, Aug 1 2025, Vol. 135.
https://doi.org/10.1016/j.reprotox.2025.108930
Toxicological impact of tetrabromobisphenol-A on pregnant rats: Morphological, biochemical, and histopathological investigations,
Özkan, M., Inkaya, E. N., Koçkaya, E. A. and Barlas, N., Toxicology and Industrial Health, May 2026, Vol. 42, no. 5, p. 178-197.
https://doi.org/10.1177/07482337261438207
Combined Exposure to Endocrine Disruptors, BPA and BP-3, during Pregnancy and Lactation Alters Postnatal Body Mass, Growth, White Adipose Tissue Morphology, and Adipogenic Gene Expression in a Sex-Specific Manner,
Raticova, K., Howanski, J., Fink, B., Roder, S., Bauer, M., Schumacher, A., Zenclussen, A. C. and Kretschmer, T., Environment & Health, 2026.
https://doi.org/10.1021/envhealth.5c00679
Exposure to Bisphenol A and Z causes DNA damage and testicular histopathology impairing male fertility,
Rehman, H. U., Nadeem, A., Mukhtar, N., Ali, M. M., Mujahid, H., Shabbir, M. Z. and Javed, M., Toxicology and Industrial Health, May 2026, Vol. 42, no. 5, p. 198-206.
https://doi.org/10.1177/07482337261438341
Female reproductive toxicity of chronic exposure to perfluorohexane sulfonate (PFHxS) under the confounding factor of dietary protein deficiency,
Suramya, S., Javed, M., Ahmad, B. and Raisuddin, S., Reproductive Toxicology, May 2026, Vol. 142.
https://doi.org/10.1016/j.reprotox.2026.109213
Écrit par Nathalie TOULEMONDE