Bulletin de veille Perturbateurs endocriniens, n°31, août 2025
Exposition professionnelle
Phthalate Metabolites and Their Relationship with Abdominal and General Obesity: Evidence from the Aragon Workers' Health Study (AWHS),Akritidis, J., Mérida, D. M., Torrijo-Belanche, C., Moreno-Franco, B., Gimeno-Ruiz, S., Rey-García, J., Morales-Suarez-Varela, M. and Guallar-Castillón, P., Nutrients, May 30 2025, Vol. 17, no. 11.
https://doi.org/10.3390/nu17111869
Phthalate Metabolites and Their Relationship with Abdominal and General Obesity: Evidence from the Aragon Workers' Health Study (AWHS).
Akritidis, J. a.-O. X., Mérida, D. a.-O., Torrijo-Belanche, C. a.-O., Moreno-Franco, B., Gimeno-Ruiz, S. a.-O., Rey-García, J. a.-O., Morales-Suarez-Varela, M. a.-O. and Guallar-Castillón, P. a.-O., no. 2072-6643 (Electronic). https://doi.org/10.3390/nu17111869
Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition - the potential cause of occupational Bisphenol-A exposition,
Bidiga, L., Csonka, T., Méhes, G., Markóth, C., Hutkai, D. and Mátyus, J., Pathol Oncol Res, 2025, Vol. 31, p. 1612046.
https://doi.org/10.3389/pore.2025.1612046
Children's environmental and occupational exposures to pesticides in low- and middle-income countries rural areas - an elephant in the room,
Buralli, R., Nazli, S. N., Cordoba, L., Quiros-Alcala, L., Hyland, C., Muñoz-Quezada, M. T., Farías, P. and Handal, A. J., no. 1879-1026 (Electronic). https://doi.org/10.1016/j.scitotenv.2025.179887
Occupational Exposure to Pesticides Among Farmworkers in Morocco: A Study Framework for Endocrine and Epigenetic Effect Assessment,
Chbihi, K., Menouni, A., Berni, I., Chetouani, H., Abou-Said, S., Amellah, A., Lebegge, R., Verscheure, E., Vanoirbeek, J., Duca, R. C., Godderis, L. and El Jaafari, S., Toxics, Apr 25 2025, Vol. 13, no. 5.
https://doi.org/10.3390/toxics13050340
Changes in serum perfluorooctane sulfonic acid and perfluorohexane sulfonic acid concentrations in firefighters accessing a voluntary perfluoroalkyl and polyfluoroalkyl substances reduction treatment program,
Delaere, I., Harris, K., Gaskin, S., Tefera, Y., Mitchell, K., Springer, D. and Mills, S., no. 1873-6750 (Electronic). https://doi.org/10.1016/j.envint.2025.109609
Per- and polyfluoroalkyl substances (PFAS) and microRNA: An epigenome-wide association study in firefighters,
Furlong, M. A., Liu, T., Jung, A., Beitel, S., Hughes, J., Krause, R., Graber, J. M., Calkins, M. M., Calafat, A. M., Botelho, J. C., Huentelman, M., Gulotta, J., Goodrich, J. M. and Burgess, J. L., Environmental Research, Aug 15 2025, Vol. 279.
https://doi.org/10.1016/j.envres.2025.121766
Occupational Benzene Exposure and Risk of Male Genital Cancers: A Systematic Review and Meta-Analysis,
Godono, A., Quattrocolo, A., Caradonna, R., Picciaiola, M. V., Boffetta, P. and Seyyedsalehi, M. S., American Journal of Industrial Medicine, Aug 2025, Vol. 68, no. 8, p. 666-678.
https://doi.org/10.1002/ajim.23740
Polybrominated diphenyl ethers (PBDEs), Occupational Exposures and Thyroid Function among U.S. and Canadian Firefighters: A Cross-sectional Study,
Gould Rothberg, B. E., Caban-Martinez, A. J., Barr, D. B., Jara, M. A., Rodriguez, V., Feliciano, P. L., Santiago, K. M., Beaver, C. C., Kobetz-Kerman, E. N. and Solle, N. S., J Occup Environ Med, Jun 5 2025.
https://doi.org/10.1097/jom.0000000000003477
Serum Concentration of Selected Per- and Polyfluoroalkyl Substances (PFAS) by Industry and Occupational Groups Among US Adult Workers, NHANES 2005-2014,
Gu, J. a.-O., Charles, L. a.-O., Lim, C. S., Mnatsakanova, A., Anderson, S., Dzubak, L. and Mccanlies, E., no. 1097-0274 (Electronic). https://doi.org/10.1002/ajim.23726
Risk of preeclampsia and gestational diabetes after occupational exposure to chemicals during pregnancy-A cohort study of births in Sweden 1994-2014,
Gustavsson, P., Lissåker, C., Albin, M., Alfredsson, L., Wiebert, P., Tinnerberg, H., Grahn, K., Rylander, L. and Selander, J., no. 1096-0953 (Electronic). https://doi.org/10.1016/j.envres.2025.121802
A Critical Review of Populations with Occupational Exposure to Per- and Polyfluoroalkyl Substances: External Exposome, Internal Exposure Levels, and Health Effects,
He, A., Liang, Y. a.-O., Li, J., Zhou, Z., Li, F., Li, Z., Wang, Y. a.-O. and Jiang, G. a.-O., no. 1520-5851 (Electronic). https://doi.org/10.1021/acs.est.4c14478
Evaluation of pesticide health risks and its associated metabolic health Status among nursery operators in Peninsular Malaysia,
How, V., Muhamad, S. N., Abdullah, R., Yu Bin, H. and Waras, M. N., no. 2154-4700 (Electronic).
https://doi.org/10.1080/19338244.2025.2522780
High serum perfluorooctanoic acid (PFOA) concentrations and interstitial lung disease in former and current workers in a fluorochemical company.
Kanetani, K., Nakamura, K., Harada, K. H., Akihisa, H., Oshima, T., Ogata, H. and Koizumi, A., no. 1880-8026 (Electronic). https://doi.org/10.2486/indhealth.2025-0009
Impact of Industrial Pollution on Human Renal Function and Male Reproductive Hormones: An Investigation of Heavy Metals Toxicity and Oxidative Stress,
Khdr, A. H. and Abdoulrahman, K., Journal of Applied Toxicology, 2025.
https://doi.org/10.1002/jat.4850
HBM4EU e-waste study - Occupational exposure assessment to chromium, cadmium, mercury and lead during e-waste recycling,
Leese, E., Verdonck, J., Porras, S. P., Airaksinen, J., Duca, R. C., Galea, K. S., Godderis, L., Janasik, B., Mahiout, S., Martins, C., Mārtiņsone, I., Ani, M. M., Van Nieuwenhuyse, A., Scheepers, P. T. J., Silva, M. J., Viegas, S. and Santonen, T., Environ Res, Oct 15 2025, Vol. 283, p. 121892.
https://doi.org/10.1016/j.envres.2025.121892
Exploratory research on occupational exposures and breast cancer risk in the CECILE study,
Leung, L. a.-O., Koushik, A. a.-O., Cordina-Duverger, E. a.-O., Siemiatycki, J. a.-O. and Guénel, P. a.-O. X., no. 1470-7926 (Electronic). https://doi.org/10.1136/oemed-2024-110021
Association between size-resolved PM(10)-bound heavy metal and metalloid exposure and oxidative stress among waste recycling workers,
Li, X. and Guo, Y., Sci Rep, Jul 16 2025, Vol. 15, no. 1, p. 25785.
https://doi.org/10.1038/s41598-025-09250-1
The effects of parental occupational exposures on autism spectrum disorder severity and skills in cognitive and adaptive domains in children with autism spectrum disorder,
Mccanlies, E. C., Gu, J. K., Ma, C. C., Sanderson, W. T., Ludeña-Rodriguez, Y. J. and Hertz-Picciotto, I., International Journal of Hygiene and Environmental Health, Jul 2025, Vol. 268.
https://doi.org/10.1016/j.ijheh.2025.114613
Occupational pesticide exposure and cognitive impairment among adult farmers in northern Thailand,
Phitsadang, N., Naksen, W. and Ong-Artborirak, P., Rocz Panstw Zakl Hig, Jun 26 2025, Vol. 76, no. 1, p. 29-37.
https://doi.org/10.32394/rpzh/200912
Epidemiology and occupational risk factors of male infertility based on 3,025 patients in Eastern Morocco during 2021-2023: a cohort study,
Rochdi, C., Ouadrhiri, M., Bellajdel, I., Taheri, H., Saadi, H., Mimouni, A. and Choukri, M., Obstetrics & Gynecology Science, May 2025, Vol. 68, no. 3, p. 198-209.
https://doi.org/10.5468/ogs.24297
Per- and polyfluoroalkyl substance emission from waste thermal treatment: A review,
Safarzadeh, H., Bonato, T., Ebrahimzadeh Sarvestani, M. and Di Maria, F., Waste Manag Res, Jul 28 2025, p. 734242x251349211.
https://doi.org/10.1177/0734242x251349211
Evaluation of pesticide residues in greenhouse workers' blood serum using QuEChERS-UHPLC-MS/MS method and associated health risks,
Salari, E., Esmaeilian, M., Faryabi, R., Mahdavi, V., Mashayekhi-Sardoo, H. and Askarpour, H., Food Chem Toxicol, Sep 2025, Vol. 203, p. 115612.
https://doi.org/10.1016/j.fct.2025.115612
Epidémiologie
Dietary intake of polycyclic aromatic hydrocarbons (PAHs) and breast cancer risk: Evidence from the French E3N-Generations prospective cohort,Amadou, A., Praud, D., Marques, C., Noh, H., Frenoy, P., Vigneron, A., Coudon, T., Deygas, F., Severi, G., Fervers, B. and Mancini, F. R., Environment International, Jun 2025, Vol. 200.
https://doi.org/10.1016/j.envint.2025.109505
Exposure to polyoxyethylene tallow amines (POEAs), glyphosate co-formulation surfactants, in a US pregnant population and their potential endocrine disrupting effects,
Amreen, B., Lesseur, C., Jagani, R., Yelamanchili, S., Barrett, E. S., Nguyen, R. H. N., Sathyanarayana, S., Swan, S. H., Andra, S. S. and Chen, J., Environmental Pollution, Jun 1 2025, Vol. 374.
https://doi.org/10.1016/j.envpol.2025.126205
Association between endocrine disrupting chemicals and female infertility: a study based on NHANES database,
Bingru, L., Ting, C., Zhe, Z., Wen, J., Qianling, Z. and Hailun, Z., Frontiers in Public Health, Jun 30 2025, Vol. 13.
https://doi.org/10.3389/fpubh.2025.1608861
Periconception bisphenol and phthalate concentrations in women and men, time to pregnancy, and risk of miscarriage,
Blaauwendraad, S. M., Boxem, A. J., Gaillard, R., Kahn, L. G., Lakuleswaran, M., Sakhi, A. K., Bekkers, E. L., Mo, Z. X., Spadacini, L., Thomsen, C., Steegers, E. a. P., Mulders, A., Jaddoe, V. W. V. and Trasande, L., Environmental Research, Aug 1 2025, Vol. 278.
https://doi.org/10.1016/j.envres.2025.121712
Phthalates and bisphenols early-life exposure, and childhood allergic conditions: a pooled analysis of cohort studies,
Boissiere-O'neill, T., Lazarevic, N., Sly, P. D., Ponsonby, A. L., Chen, A. M., Azad, M. B., Braun, J. M., Brook, J. R., Burgner, D., Lanphear, B. P., Moraes, T. J., Saffery, R., Subbarao, P., Turvey, S. E., Yolton, K., Vilcins, D., Grp, C. I. and Grp, B. I. S. I., Journal of Exposure Science and Environmental Epidemiology, 2025.
https://doi.org/10.1038/s41370-025-00790-2
Associations between environmental chemical mixtures and anthropometric measures in Korean girls: a cross-sectional study,
Bolormaa, E., Kim, K., Jhang, H., Cho, Y. M., Enkhbat, U. and Choe, S. A., European Journal of Pediatrics, Jun 16 2025, Vol. 184, no. 7.
https://doi.org/10.1007/s00431-025-06255-w
Mixtures of chemicals in pregnancy and their effects on cognitive and fine motor abilities in childhood,
Brennan Kearns, P., González, L., Soler-Blasco, R., Andiarena, A., Santa-Marina, L., Casas, M., Burgaleta, M., Vrijheid, M. and Guxens, M., Environ Res, Jul 19 2025, Vol. 285, no. Pt 2, p. 122380.
https://doi.org/10.1016/j.envres.2025.122380
Endocrine disrupting chemicals exposure and health: An umbrella review,
Chen, J. H., Song, P., Li, C., Liu, H. J., Zhang, L., Zhou, Y., Zhou, Z. and Yan, W. G., Ecotoxicology and Environmental Safety, Sep 1 2025, Vol. 302.
https://doi.org/10.1016/j.ecoenv.2025.118574
Association between per- and polyfluoroalkyl substances and unexplained recurrent spontaneous abortion: A case-control study in China,
Cheng, Q., Lv, C., Li, Y., Song, H., Li, S., Li, D., Han, Y., Zhao, F. and Lin, Q., Ecotoxicology and Environmental Safety, 2025/08/01/ 2025, Vol. 301, p. 118496.
https://doi.org/https://doi.org/10.1016/j.ecoenv.2025.118496
Early-life exposure to organophosphate esters and child neurodevelopment in the French national birth cohort,
Chupeau, Z., Mercier, F., Bot, B. L., Siméon, T., Chauvet, G., Bonvallot, N., Zaros, C., Charles, M. A., Glorennec, P. and Chevrier, C., no. 1873-6750 (Electronic). https://doi.org/10.1016/j.envint.2025.109558
Phenol biomarker concentrations in human ovarian follicular fluid and the associations with in-vitro fertilization outcomes,
Dimitriadis, I., Souter, I., Williams, P. L., Weller, D., Ford, J. B., Hauser, R. and Mínguez-Alarcón, L., International Journal of Hygiene and Environmental Health, Jul 2025, Vol. 268.
https://doi.org/10.1016/j.ijheh.2025.114617
Co-exposure of phthalates, bisphenols, parabens, and polycyclic aromatic hydrocarbons in follicular fluid of women undergoing assisted reproductive technologies and the associations with hormone levels,
Dou, X. Y., Li, X. L., Huang, S. Y., Long, C. Y., Chen, C. R., Chen, X. and Yu, Y. X., Journal of Environmental Exposure Assessment, Jun 2025, Vol. 4, no. 2.
https://doi.org/10.20517/jeea.2025.07
Hair as an Indicator of Prolonged Paraben Exposure and Its Relation to Weight Gain in a Sample of Spanish Children: A Proof-of-Concept Study,
Gálvez-Ontiveros, Y., González-Palacios, P., Ramírez, V., Monteagudo, C., Samaniego-Sánchez, C., Rivas, A. and Zafra-Gómez, A., Nutrients, May 6 2025, Vol. 17, no. 9.
https://doi.org/10.3390/nu17091593
Association of Organochlorine Pesticide Exposure as Endocrine Disruptors with Polycystic Ovarian Syndrome in North India,
Garg, R., Goswami, B., Singh, K., Singh, S., Agrawal, P., Gupta, P. and Verma, U., Journal of Mid-Life Health, Apr-Jun 2025, Vol. 16, no. 2, p. 201-207.
https://doi.org/10.4103/jmh.jmh_50_25
Prenatal exposures to persistent organic pollutants and menstrual characteristics in girls at age 12 in the French PELAGIE cohort,
Génard-Walton, M., Angot, E., Warembourg, C., Monfort, C., Rouget, F., Costet, N., Tillault, H., Lainé, F., Gaudreau, É., Cordier, S., Kvaskoff, M., Chevrier, C. and Garlantézec, R., Environ Res, Aug 5 2025, Vol. 285, no. Pt 3, p. 122445.
https://doi.org/10.1016/j.envres.2025.122445
Bisphenol A exposure and behavioral outcomes in children: A systematic review and meta-analysis of evidence limited to the BASC assessment tool,
González-Palacios, P., Ramírez, V., Monteagudo, C., Zafra-Gómez, A. and Rivas, A., Neuroscience and Biobehavioral Reviews, Sep 2025, Vol. 176.
https://doi.org/10.1016/j.neubiorev.2025.106274
Maternal exposure to pesticides and gestational diabetes mellitus in the Elfe cohort,
Guesdon, L., Warembourg, C., Chevrier, C., De Lauzon-Guillain, B., Caudeville, J., Charles, M. A., Le Lous, M., Blanc-Petitjean, P. and Béranger, R., Environmental Research, Nov 1 2025, Vol. 284.
https://doi.org/10.1016/j.envres.2025.122275
Sex-specific associations of the endocrine-disrupting chemicals with serum neurofilament light chain among US adults,
Hong, K. T., Cheng, H. Y., Zhuang, Y. and Yu, Y. X., Ecotoxicology and Environmental Safety, Jun 15 2025, Vol. 298.
https://doi.org/10.1016/j.ecoenv.2025.118272
Endocrine and Reproductive Health Considerations of Sunscreen UV Filters: Insights from a Comprehensive Review 2014-2024,
Jaskulak, M., Cinkusz, M., Franchuk, K. and Zorena, K., Curr Environ Health Rep, Aug 2 2025, Vol. 12, no. 1, p. 28.
https://doi.org/10.1007/s40572-025-00492-9
Understanding the role of endocrine disrupting chemicals as environmental obesogens in the obesity epidemic: A comprehensive overview of epidemiological studies between 2014 and 2024,
Jaskulak, M., Zimowska, M., Rolbiecka, M. and Zorena, K., Ecotoxicology and Environmental Safety, Jul 1 2025, Vol. 299.
https://doi.org/10.1016/j.ecoenv.2025.118401
Associations of urinary organophosphate ester metabolites with bone mineral density in US children and adolescents aged 8-19 years: a cross-sectional study based on NHANES 2011-2018,
Jin, H. L., Zhou, X. Y., Wang, X. Y. and Zhang, Y., European Journal of Pediatrics, Jun 4 2025, Vol. 184, no. 7.
https://doi.org/10.1007/s00431-025-06235-0
Paraben exposure profiles in pregnant women and association with changes in thyroid hormone levels,
Khelfi, A., Idjeraoui, A., Ouarzidini, H., Aksas, K., Makrelouf, M., Cherifi, M. and Azzouz, M., no. 2213-3941 (Electronic). https://doi.org/10.1016/j.ando.2025.101801
Exposome-wide association study of sex-steroid hormones in the US general population: evaluation of complex mixture effects☆,
Lee, J., Jang, H. and Shin, H. M., Environmental Pollution, Sep 1 2025, Vol. 380.
https://doi.org/10.1016/j.envpol.2025.126533
Prenatal exposure to polyfluoroalkyl substances and visual acuity in preschool children: Findings from the Guangxi Zhuang birth cohort in China,
Lei, L. D., Lv, F. F., Lu, P. N., Mo, C. M., Li, J. X., Xu, X. M., Wei, G. J., Huang, X. Q., Qiu, X. Q., Huang, D. P., Zhou, X. M., Wei, H., Zeng, X. Y. and Liu, S., Ecotoxicology and Environmental Safety, Jul 15 2025, Vol. 300.
https://doi.org/10.1016/j.ecoenv.2025.118477
Association of urine parabens with liver function in US adolescents based on NHANES 2007-2016,
Li, L. F., Hu, G. C., Luo, X., Wei, Z. X. and He, J., Scientific Reports, Jul 1 2025, Vol. 15, no. 1.
https://doi.org/10.1038/s41598-025-08435-y
The association between brominated flame retardants and serum testosterone levels in American adult men: NHANES 2013-2016,
Li, X., Chen, M., Zheng, Q., Wang, Z., Lin, D. and Peng, M., Front Public Health, 2025, Vol. 13, p. 1589047.
https://doi.org/10.3389/fpubh.2025.1589047
Association between ovarian reserve and organophosphate flame retardants in women of childbearing age,
Lien, H. T., Ou, Y. C., Cheng, Y. H., Kung, C. T., Chang, Y. C., Weng, P. L. and Lan, K. C., Taiwanese Journal of Obstetrics & Gynecology, May 2025, Vol. 64, no. 3, p. 504-511.
https://doi.org/10.1016/j.tjog.2024.11.012
Associations between organophosphate flame retardants and risk for nonsyndromic cleft lip and/or palate in offspring,
Lin, S. J., Li, S. N., Cheng, Q. H., Ding, Y. Q., Chen, Y. Y., Liu, J. F., Jin, L., Li, Z. W., Ren, A. G. and Wang, L. L., Environmental Sciences Europe, Jun 22 2025, Vol. 37, no. 1.
https://doi.org/10.1186/s12302-025-01150-5
Evaluating the relationship between environmental chemicals and obesity: Evidence from a machine learning perspective,
Liu, H., Gu, H. W., Li, J., Fang, Y. F., Yang, S. and Liang, G. Y., Ecotoxicology and Environmental Safety, Jul 15 2025, Vol. 300.
https://doi.org/10.1016/j.ecoenv.2025.118457
The significance of organophosphate flame retardants in patients with esophageal squamous cell carcinoma,
Lu, H. I., Huang, W. T., Lee, W. C., Cheng, F. J., Kung, C. T., Wang, C. C., Wang, L. J., Ou, Y. C. and Li, S. H., Environmental Geochemistry and Health, Jul 2025, Vol. 47, no. 7.
https://doi.org/10.1007/s10653-025-02599-2
Per-and Polyfluoroalkyl Substances in Eutopic Endometrium Tissue and Risk of Endometriosis: Findings from the Investigating Mixtures of Pollutants and Endometriosis in Tissue (IMPLANT) Study,
Marroquin, J. M., Krall, J. R., Schliep, K. C., Farland, L. V., Krishnamoorthi, V., Kannan, K. and Pollack, A. Z., Environmental Health Perspectives, Jun 2025, Vol. 133, no. 6.
https://doi.org/10.1289/ehp15852
Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 diabetes and metabolic pathway dysregulation in a multiethnic US population,
Midya, V., Yao, M., Colicino, E., Barupal, D., Lin, X., Gennings, C., Chatzi, L., Setiawan, V. W., Loos, R. J. F., Walker, R. W., Walker, D. I. and Valvi, D., EBioMedicine, Aug 2025, Vol. 118, p. 105838.
https://doi.org/10.1016/j.ebiom.2025.105838
Associations between urinary phthalate metabolite mixtures, semen quality, and serum reproductive hormone levels in Japanese men seeking fertility treatment,
Mizuno, Y., Yamasaki, K., Uchida, M., Iwamoto, T. and Konishi, S., Reproductive Toxicology, Sep 2025, Vol. 136, p. 8.
https://doi.org/10.1016/j.reprotox.2025.108957
Per- and polyfluoroalkyl substance concentrations during pregnancy and at birth and risk of childhood acute lymphoblastic leukemia,
Morimoto, L. M., Metayer, C., Dolios, G., Wiemels, J. L., Ma, X., Guan, H., Maroli, A. and Petrick, L. M., Environ Res, Jul 25 2025, Vol. 285, no. Pt 3, p. 122436.
https://doi.org/10.1016/j.envres.2025.122436
Prenatal exposure to phthalates and alternative plasticizers and emotional and behavioral outcomes in early childhood in the Environmental influences on Child Health outcomes (ECHO) cohort,
Oh, J., Buckley, J. P., Upadhyaya, S., Kannan, K., Barrett, E. S., Bastain, T. M., Breton, C., Eick, S. M., Geiger, S. D., Ghassabian, A., Habre, R., Herbstman, J. B., Hirtz, D., Liang, D. H., Lewinn, K., Meeker, J. D., O'connor, T. G., Hertz-Picciotto, I., Ruden, D., Sathyanarayana, S., Schantz, S. L., Schweitzer, J. B., Sigal, A., Woodruff, T. J., Zhao, Q., Schmidt, R. J., Bennett, D. H. and Consortium, E. C., Environment International, Aug 2025, Vol. 202.
https://doi.org/10.1016/j.envint.2025.109647
Sex-specific effects of prenatal exposure to phthalates and bisphenol A on adverse birth outcomes: Results from The Korean CHildren's ENvironmental health Study (Ko-CHENS),
Oh, J., Shah, S., Lee, K. A., Park, E., Lee, D. W., Hong, Y. C., Song, S., Kim, S. Y., Park, H., Kim, H. C., Jeong, K. S., Ha, E. and Ko, C. S. G., Environment International, May 2025, Vol. 199.
https://doi.org/10.1016/j.envint.2025.109518
Association of Per- and Polyfluoroalkyl Substances with Pan-Cancers Associated with Sex Hormones,
Olarewaju, E. and Obeng-Gyasi, E., Toxics, Jun 14 2025, Vol. 13, no. 6.
https://doi.org/10.3390/toxics13060501
The relationship between metabolic syndrome and environmental endocrine disruptors: A systematic review and meta-analysis,
Pan, K., Xu, J., Li, F., Aris, A. Z., Yu, H., Xu, Y., He, J., Wang, C. and Yu, J., iScience, Jul 18 2025, Vol. 28, no. 7, p. 112907.
https://doi.org/10.1016/j.isci.2025.112907
Plasticizer exposure and reproductive dysfunction: Assessing bisphenol A and phthalate esters impact on ovarian reserve in women with PCOS-associated infertility,
Patel, J., Chaudhary, H., Panchal, S. and Joshi, R., Reproductive Toxicology, Aug 2025, Vol. 135.
https://doi.org/10.1016/j.reprotox.2025.108949
Brain Abnormalities in Children Exposed Prenatally to the Pesticide Chlorpyrifos,
Peterson, B. S., Delavari, S., Bansal, R., Sawardekar, S., Gupte, C., Andrews, H., Hoepner, L. A., Garcia, W., Perera, F. and Rauh, V., JAMA Neurology, 2025.
https://doi.org/10.1001/jamaneurol.2025.2818
Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe
Shirke, A. a.-O., Radke, E. G., Jones, R., Allen, B. a.-O., Lin, C. a.-O., Ross, A. a.-O., Vetter, N. a.-O. X., Lemeris, C. a.-O., Hartman, P., Eftim, S. a.-O., Varghese, A. a.-O. X., Blain, R. a.-O., Hubbard, H. a.-O., Williams, A. a.-O., Thayer, K. a.-O. X. and Carlson, L. a.-O., no. 1552-9924 (Electronic). https://doi.org/10.1289/EHP16952
Bisphenol A in the Urine: Association with Urinary Creatinine, Impaired Kidney Function, Use of Plastic Food and Beverage Storage Products but Not with Serum Anti-Müllerian Hormone in Ovarian Malignancies,
Sladic, M., Smrkolj, S., Kavsek, G., Imamovic-Kumalic, S., Verdenik, I. and Virant-Klun, I., International Journal of Molecular Sciences, May 17 2025, Vol. 26, no. 10.
https://doi.org/10.3390/ijms26104811
Exposure to persistent organic pollutants and sarcopenia: Revealing associations, mediated modifications, and potential mechanisms,
Tao, J., Zhai, J., Yang, J., Niu, Q., Hu, Y. and Yan, Y., Ecotoxicol Environ Saf, Aug 5 2025, Vol. 303, p. 118783.
https://doi.org/10.1016/j.ecoenv.2025.118783
Elevated follicular fluid concentrations of ultraviolet filters associated with diminished ovarian reserve: A case-control study,
Tian, Y. C., Sun, J. L., Fang, Y., Li, C., Wang, C., Xin, Z. M., Wang, S. and Yang, X. K., Environment International, Jul 2025, Vol. 201, p. 10.
https://doi.org/10.1016/j.envint.2025.109573
Associations Between Endocrine-Disrupting Chemical Exposure and Fertility Outcomes: A Decade of Human Epidemiological Evidence,
Tzouma, Z., Dourou, P., Diamanti, A., Harizopoulou, V., Papalexis, P., Karampas, G., Liepinaitienė, A., Dėdelė, A. and Sarantaki, A., Life (Basel), Jun 21 2025, Vol. 15, no. 7.
https://doi.org/10.3390/life15070993
Poly-and perfluoroalkyl substances (PFAS) in the first 1000 days reduce linear growth, lean body mass and bone mineral density at age 3 years,
Van Beijsterveldt, I., Dorrepaal, D. J., Van Zelst, B. D., Van Den Berg, S. a. A. and Hokken-Koelega, A. C. S., Clinical Nutrition, Jul 2025, Vol. 50, p. 175-182.
https://doi.org/10.1016/j.clnu.2025.05.017
Prenatal exposure to bisphenol-A and neurocognitive changes in children aged 2 to 5 years: a systematic review,
Vian Matias De Oliveira, I., Martins De Albuquerque, F., De Jesus Fernandes, A., Berti Zanella, P. and Alves Silva, M., Rev Environ Health, Aug 5 2025.
https://doi.org/10.1515/reveh-2024-0161
Early life phthalate exposure impacts gray matter and white matter volume in infants and young children,
Werder, E. J., Lu, K., Liu, C. W., Thistle, J. E., Rager, J. E., Li, G., Wu, Z. W., Li, T. F., Wang, L., Sandler, D. P., Gilmore, J. H., Piven, J., Zhu, H. T., Lin, W. L. and Engel, S. M., Environmental Research, Aug 15 2025, Vol. 279.
https://doi.org/10.1016/j.envres.2025.121826
Association between phthalate exposure and reproductive health in patients undergoing assisted reproductive treatment: A systematic review and meta-analysis,
Xie, G. M., Zhou, Y. J., Zheng, Q. Y., Wang, L., Wang, Y., Zeng, H. J., Wang, J. L. and Li, X. Y., Reproductive Toxicology, Sep 2025, Vol. 136.
https://doi.org/10.1016/j.reprotox.2025.108948
Association of prenatal exposure to phthalates with risks of asthma, wheeze, and allergic diseases during childhood: a systematic review and meta-analysis,
Yang, J., Zhang, M., Luo, J., Pan, J., Luo, T. and Yang, W., J Environ Health Sci Eng, Dec 2025, Vol. 23, no. 2, p. 26.
https://doi.org/10.1007/s40201-025-00951-3
Exposure to Dioxin-like polychlorinated biphenyls during Pregnancy and fetal thyroid function; A mixture analysis,
Yu, Y., Wu, B., Li, Z., Hu, Y., Zhang, D. and Yang, C., Ecotoxicol Environ Saf, Sep 1 2025, Vol. 302, p. 118646.
https://doi.org/10.1016/j.ecoenv.2025.118646
Association between endocrine disrupting chemicals exposure and the risk of all-cause mortality in individuals with diabetes mellitus or its complications: A prospective cohort study,
Zhang, Y. H., Zhang, Z. L., Zhou, F. Y., Xu, G. C., Huang, W. C., Wang, M. Y., Lan, Y. Q., Zhang, W., Liu, Z. Y., Chang, S. S., Qiu, S., Qi, F. and Wei, Z. R., Environment International, Jun 2025, Vol. 200.
https://doi.org/10.1016/j.envint.2025.109556
The causal role of endocrine disrupting chemicals in pubertal timing: a Mendelian randomization study,
Zuo, M., Gamache, I., Fagbemi, K., Day, F. R., Ong, K. K. and Manousaki, D., Journal of Pediatric Endocrinology & Metabolism, Jul 28 2025, Vol. 38, no. 7, p. 753-760.
https://doi.org/10.1515/jpem-2025-0146
Toxicité sur l’homme
Redefining the pathogenesis of Gestational Diabetes Mellitus: The cumulative impact of endocrine disrupting environmental chemicals in key metabolic pathways,Aayush, M. V., Nikthesh, G., Rajmohan, D., Ravindran, C. P., Vasantharekha, R., Thangavelu, S. and Seetharaman, B., Medical Hypotheses, Aug 2025, Vol. 201.
https://doi.org/10.1016/j.mehy.2025.111693
RNA-Seq Uncovers Association of Endocrine-Disrupting Chemicals with Hub Genes and Transcription Factors in Aggressive Prostate Cancer,
Alwadi, D., Felty, Q., Doke, M., Roy, D., Yoo, C. and Deoraj, A., International Journal of Molecular Sciences, Jun 6 2025, Vol. 26, no. 12.
https://doi.org/10.3390/ijms26125463
Non-occupational exposure to cadmium and breast cancer: A comprehensive and critical review,
Anicic, R., Zekovic, M., Kocic, M., Gluvic, Z., Manojlovic, D., Scancar, J. and Stojsavljevic, A., Ecotoxicology and Environmental Safety, Jun 15 2025, Vol. 298.
https://doi.org/10.1016/j.ecoenv.2025.118331
Can Bisphenols Alter the Inflammation Process?,
Bazany, D., Greifova, H., Zuscikova, L., Tokarova, K., Jambor, T., Kovacik, A. and Lukac, N., Life-Basel, May 14 2025, Vol. 15, no. 5.
https://doi.org/10.3390/life15050782
Bisphenol A drives nuclear factor-kappa B signaling activation and enhanced motility in non-transformed breast cells,
Citarella, A., Besharat, Z. M., Coppola, L., Sabato, C., Autilio, T. M., Vicentini, E., Bimonte, V. M., Catanzaro, G., Pediconi, N., Fabi, A., Migliaccio, S., Milella, M., Bei, R. B. R., Ferretti, E. and Po, A. G. S., Environmental Pollution, Jul 1 2025, Vol. 376.
https://doi.org/10.1016/j.envpol.2025.126422
Étude de l’influence des polluants environnementaux sur l’incidence du diabète de type 2. Thèse présentée en vue de l’obtention du grade de Doctorat en Sciences Biomédicales et Pharmaceutiques,
Claessens, J., Université de Liège (2025),
https://orbi.uliege.be/bitstream/2268/335437/1/These%20VF%20Julien%20Claessens%20.pdf
Obesity and obesity related disease in adulthood: the dark side of early life exposure to Environmental Chemical Disruptors,
Di Lorenzo, M., Aurino, L., Lonardo, M. S., Cacciapuoti, N., Nasti, G., Belfiore, A., Guida, B. and Chiurazzi, M., Journal of Endocrinological Investigation, 2025.
https://doi.org/10.1007/s40618-025-02620-6
Intergenerational and transgenerational effects of endocrine-disrupting chemicals in the offspring brain development and behavior,
Dias, G. R. M., Giusti, F. C. V., De Novais, C. O., De Oliveira, M. a. L., Paiva, A. G., Kalil-Cutti, B., Mahoney, M. M. and Graceli, J. B., Frontiers in Endocrinology, May 21 2025, Vol. 16.
https://doi.org/10.3389/fendo.2025.1571689
Ultra-Processed Diets and Endocrine Disruption, Explanation of Missing Link in Rising Cancer Incidence Among Young Adults,
Fajkic, A., Lepara, O., Jahic, R., Hadzovic-Dzuvo, A., Belancic, A., Chupin, A., Pavkovic, D. and Sher, E. K., Cancers, Jun 29 2025, Vol. 17, no. 13.
https://doi.org/10.3390/cancers17132196
Shared molecular mechanisms of bisphenol A and phthalates in endometriosis: A bioinformatics and molecular docking study,
Fan, Z. X., Maisaidi, R., Reheman, Y., Li, Y., Zhou, P. L. and Han, L. L., Ecotoxicology and Environmental Safety, Jul 1 2025, Vol. 299.
https://doi.org/10.1016/j.ecoenv.2025.118388
Mechanisms of di (2-Ethylhexyl) Phthalate-Induced Lipid Metabolism Disorders: A Review,
Fang, X., Wang, T., Lou, S., Qiao, Y., Zhang, B. and Zhou, L., J Appl Toxicol, Jul 28 2025.
https://doi.org/10.1002/jat.4867
The effect of phthalates on insulin secretion of pancreatic beta cells based on cellular studies, a systematic review,
Ghanati, K., Pourjafar, H., Shavali-Gilani, P., Akbari, N., Tavoosidana, G., Zandsalimi, F., Abdolhosseini, M., Aghaei, M. and Sadighara, P., Toxicology Letters, Jul 2025, Vol. 410, p. 76-82.
https://doi.org/10.1016/j.toxlet.2025.06.002
Liver Toxicity Induced by Exposure to Bisphenol Analogs at Environmentally Relevant Levels: Insights from a Literature Review on Multiple Species,
Guo, T. L., Eldefrawy, F. and Guo, K. M., Livers, May 27 2025, Vol. 5, no. 2.
https://doi.org/10.3390/livers5020024
The Presence of Microplastics in Human Semen and Their Associations with Semen Quality,
Guo, Y., Rong, M., Fan, Y., Teng, X., Jin, L. and Zhao, Y., Toxics, Jul 3 2025, Vol. 13, no. 7.
https://doi.org/10.3390/toxics13070566
Integrative causal and single-cell analyses reveal genes responsive to endocrine disruptors driving human male infertility,
Hong, Y., Wang, Y., Li, J., Shu, W., Chen, H. and Chen, C., Ecotoxicol Environ Saf, Sep 1 2025, Vol. 302, p. 118709.
https://doi.org/10.1016/j.ecoenv.2025.118709
Integrative causal inference illuminates gene-environment interactions linking endocrine disruptors to female infertility,
Hong, Y. G., Du, Z. Y., Li, J. J., Wang, Y., Wang, Y. R., Shu, W. Y., Shen, Q. X., Chen, F. and Li, S. S., Ecotoxicology and Environmental Safety, Sep 1 2025, Vol. 302.
https://doi.org/10.1016/j.ecoenv.2025.118679
Per-and polyfluoroalkyl substances (PFAS) in milk and dairy products: a literature review of the occurrence, contamination sources, and health risks,
Hossini, H., Massahi, T., Parnoon, K. and Nouri, M., Food Addit Contam Part A Chem Anal Control Expo Risk Assess, Jul 28 2025, p. 1-13.
https://doi.org/10.1080/19440049.2025.2538224
Human endocrine disruption: an updated review of toxicological insights into parabens and phthalates,
Isaac, R. a. A., Subbarayalu, R., Kumar, M. S. K., Martin, T. M., Lo, S. C. and Santosh, W., Toxicology and Environmental Health Sciences, 2025.
https://doi.org/10.1007/s13530-025-00264-w
Exploring the relationship between the androgen receptor and structural configuration of benzophenones: a combination of computational analysis and laboratory models,
Jeong, D., Pathak, R. K., Jung, D. W., Kim, J. M. and Lee, H. S., Environment International, Aug 2025, Vol. 202.
https://doi.org/10.1016/j.envint.2025.109632
Exploring the Role of Bifenthrin in Recurrent Implantation Failure and Pregnancy Loss Through Network Toxicology and Molecular Docking,
Jiang, S. Y., Wang, Y. X., Chen, H. Y., Teng, Y. Y., Zhu, Q. Y. and Xie, K. P., Toxics, May 29 2025, Vol. 13, no. 6.
https://doi.org/10.3390/toxics13060454
Polyethylene and Polyvinyl Chloride Nanoplastics in Human Follicular Fluid and Seminal Plasma: Impact on Fertilization and Sperm Quality,
Kong, F., Fang, L., Gui, Y., Lan, H., Zhao, P., Zhang, Y., Jiang, L., Zhang, S. and Tong, X., ACS Nano, Aug 5 2025, Vol. 19, no. 30, p. 27159-27172.
https://doi.org/10.1021/acsnano.5c00918
Epidemiologically relevant phthalate mixture and mono (2-ethyl-5-hydroxyhexyl) phthalate exposure alter cell energy metabolism in primary mouse granulosa cells,
Laws, M. J., Kramer, S., Gonyea, T., Huff, J., Edwards, L., Tarvainen, I., Damdimopoulou, P. and Flaws, J. A., Reproductive Toxicology, Aug 2025, Vol. 135.
https://doi.org/10.1016/j.reprotox.2025.108938
Impact of endocrine disrupting chemicals (EDCs) on epigenetic regulation in the uterus: a narrative review,
Liang, Y. J., Lu, Q. S., Chen, M. J., Zhao, X. M., Chu, C., Zhang, C. F., Yuan, J. H., Liu, H. M. and Lash, G. E., Reproductive Biology and Endocrinology, May 26 2025, Vol. 23, no. 1.
https://doi.org/10.1186/s12958-025-01413-z
Novel insights into the causal relationship between endocrine-disrupting chemicals and breast cancer mediated by circulating metabolites,
Lin, Y. L., Zhang, Y., She, J., Zhao, R. D., Lin, S. J., Zhang, Y., Zhang, L. Y., Wei, J., Lin, Y. and Yang, Q. M., Environmental Pollution, Jun 15 2025, Vol. 375.
https://doi.org/10.1016/j.envpol.2025.126349
Prostate cancer and pollution: Dangerous connections,
Magnifico, S., Hinault-Boyer, C., Bost, F. and Chevalier, N., Annales D Endocrinologie, Jun 2025, Vol. 86, no. 3.
https://doi.org/10.1016/j.ando.2025.101769
Glyphosate and AMPA-induced apoptosis and epigenetic alterations in HepG2 Cells: Upregulation of p53-BAX-CASP pathways,
Mehtiyev, T., Guler, Z. R., Aktan, E. and Ozden, S., Food and Chemical Toxicology, Sep 2025, Vol. 203.
https://doi.org/10.1016/j.fct.2025.115605
An in silico to in vivo approach identifies retinoid-X receptor activating tert-butylphenols used in food contact materials,
Mengeling, B. J., Ramaprasad, A. S. E., Smith, M. T., Turkieh, D., Kleinstreuer, N. C., Mansouri, K., Durkin, K. A., La Merrill, M. A. and Furlow, J. D., Scientific Reports, Jul 18 2025, Vol. 15, no. 1.
https://doi.org/10.1038/s41598-025-09244-z
Dysregulation of microRNA (miRNA) Due to Phthalate/Phthalate Metabolite Exposure and Associated Health Effects: A Narrative Review,
Mohammed, A., Atkin, S. L. and Brennan, E., Journal of Xenobiotics, May 12 2025, Vol. 15, no. 3.
https://doi.org/10.3390/jox15030072
Unraveling the Core of Endometriosis: The Impact of Endocrine Disruptors,
Moustakli, E., Potiris, A., Grigoriadis, T., Zikopoulos, A., Drakaki, E., Zouganeli, I., Theofanakis, C., Gerede, A., Zachariou, A., Domali, E., Drakakis, P. and Stavros, S., Int J Mol Sci, Aug 6 2025, Vol. 26, no. 15.
https://doi.org/10.3390/ijms26157600
Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: A Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos,
Nishie, T., Taya, T., Omori, S., Ueno, K., Okamoto, Y., Higaki, S., Oka, M., Mitsuishi, Y., Tanaka, T., Nakamoto, M., Kawahara, H., Teraguchi, N., Kotaka, T., Sawabe, M., Takahashi, M., Kitaike, S., Wada, M., Iida, K., Yamashita, A., Jinno, H., Ichimura, A., Tooyama, I., Sakai, N., Hibi, M., Hirasawa, A. and Takada, T., Environmental Health Perspectives, Jun 2025, Vol. 133, no. 6.
https://doi.org/10.1289/ehp15574
Implications of plastic-derived endocrine disruptors on human health,
Ojo, A. B., Agbeye, O. D., Ogwa, T. O., Adedoyin, D., Rotimi, D. E. and Ojo, O. A., Toxicology Mechanisms and Methods, 2025.
https://doi.org/10.1080/15376516.2025.2510525
Environmental endocrine disruptors: rethinking the origins of early-onset ER(+) breast cancer,
Parrish, M. and Kuperwasser, C., Nat Rev Cancer, Jul 22 2025.
https://doi.org/10.1038/s41568-025-00854-3
Bisphenol A and reproductive health: a comprehensive overview of toxicological effect,
Reyaz, A., Javaid, D., Qadri, S. S., Ganie, S. Y. and Reshi, M. S., Toxicological Research, 2025.
https://doi.org/10.1007/s43188-025-00305-z
Zearalenone and its metabolites provoke contrasting modulatory responses on estrogen and androgen receptors: Insights into the molecular basis of endocrine disruption in live cells,
Rizvi, S., Chhabra, A., Sagurthi, S. R. and Tyagi, R. K., Food and Chemical Toxicology, Sep 2025, Vol. 203, p. 16.
https://doi.org/10.1016/j.fct.2025.115593
Differential susceptibility of Leydig and Sertoli cells to bisphenol A,
Ryu, D., Pang, W. K., Rahman, M. S., Park, Y. J. and Pang, M. G., Toxicology, Sep 2025, Vol. 516.
https://doi.org/10.1016/j.tox.2025.154182
Potential effects of environmental toxicants on sperm quality and potential risk for fertility in humans,
Sciorio, R., Greco, P. F., Greco, E., Tramontano, L., Elshaer, F. M. and Fleming, S., Frontiers in Endocrinology, May 21 2025, Vol. 16.
https://doi.org/10.3389/fendo.2025.1545593
Estrogenic and transgenerational effects of perfluorocarboxylic acids through estrogen-related receptor γ pathway,
Shi, S., Zheng, W., Zhang, X. L., Li, M. J., Ye, C., Chen, L., Hong, W. J., Li, C. H., Chi, H. Y., Li, F. F. and Guo, L. H., Journal of Hazardous Materials, Sep 5 2025, Vol. 495.
https://doi.org/10.1016/j.jhazmat.2025.138994
Interference with systemic negative feedback as a potential mechanism for nonmonotonic dose-responses of endocrine-disrupting chemicals,
Shi, Z. Z., Xiao, S. and Zhang, Q., Toxicological Sciences, Aug 2025, Vol. 206, no. 2.
https://doi.org/10.1093/toxsci/kfaf060
Exploring the toxicological network in diabetic microvascular disease,
Song, S. Y., Huang, L. J., Zhou, X. Q. and Yu, J. Y., International Journal of Surgery, Jun 2025, Vol. 111, no. 6, p. 3895-3907.
https://doi.org/10.1097/js9.0000000000002394
Burden of per- and polyfluoroalkyl substances (PFAS) in human breast milk: Implications for maternal and infant health,
Su, J. H., Gao, Y. R., Sun, Y. M., Bing, M. Y., Liu, Q. S., Zhou, Q. F., Fiedler, H. and Jiang, G. B., Environment International, Jul 2025, Vol. 201.
https://doi.org/10.1016/j.envint.2025.109593
Molecular insights into the interaction mechanism of endocrine-disrupting chemicals and DNA in laccase-induced polymerization transfer,
Sun, K., Shi, Z. Y., Dai, L. Z., Si, Y. B., Ma, J. C., Lin, H. and Yu, H. Q., Pnas Nexus, May 2025, Vol. 4, no. 5.
https://doi.org/10.1093/pnasnexus/pgaf148
Bisphenol A Promotes the Progression of Hormone-Sensitive Breast Cancers Through Several Inflammatory Pathways,
Thoene, M., Zglejc-Waszak, K., Jozwik, M. and Wojtkiewicz, J., Cancers (Basel), Jul 17 2025, Vol. 17, no. 14.
https://doi.org/10.3390/cancers17142373
Release of Bisphenol A from Dental Materials: Risks and Future Perspectives,
Tichy, A., Srolerova, T. and Schwendicke, F., Journal of Dental Research, Sep 2025, Vol. 104, no. 10, p. 1051-1060.
https://doi.org/10.1177/00220345251337728
The impact of bisphenol A and its analogs on female reproductive health,
Trela-Kobedza, E. and Ajduk, A., Reproductive Biology, Sep 2025, Vol. 25, no. 3.
https://doi.org/10.1016/j.repbio.2025.101028
Micro- and Nanoplastics as Disruptors of the Endocrine System-A Review of the Threats and Consequences Associated with Plastic Exposure,
Tyc, H. J., Klodnicka, K., Teresinska, B., Karpinski, R., Flieger, J. and Baj, J., International Journal of Molecular Sciences, Jun 26 2025, Vol. 26, no. 13.
https://doi.org/10.3390/ijms26136156
The sources, distribution and toxicological effects on humans of polyhalogenated carbazoles (PHCZs) as a novel pollutant,
Wang, X. X., Zhang, D. J., Liu, S. Y., Xin, H., Guan, J. L., Zhang, Y. F. and Zhang, R., Ecotoxicol Environ Saf, Aug 1 2025, Vol. 303, p. 118793.
https://doi.org/10.1016/j.ecoenv.2025.118793
Exploring thyroid development and function: A systems biology search for new chemical disruptor targets,
Zenzeluk, J., Oliveira, J. M., Sater, A. C., Bargi-Souza, P., Romano, M. A., Serrano-Nascimento, C. and Romano, R. M., Molecular and Cellular Endocrinology, Sep 15 2025, Vol. 607.
https://doi.org/10.1016/j.mce.2025.112609
Mechanisms and rescue measures of female ovarian dysfunction induced by environmental endocrine chemicals: A review,
Zhang, J. L., Zhang, N., Mai, Q. Y. and Zhou, C. Q., Reproductive Toxicology, Aug 2025, Vol. 135.
https://doi.org/10.1016/j.reprotox.2025.108954
Impact of endocrine disrupting chemicals on macrophages at the maternal-fetal interface,
Zhao, B., Lu, Q. S., Chen, M. J. and Lash, G. E., Seminars in Immunopathology, Jul 16 2025, Vol. 47, no. 1.
https://doi.org/10.1007/s00281-025-01055-8
Evaluation de l’exposition
Persistent organic pollutants in human milk of Belgian mothers: levels, time trend and exposure assessment for nursing infants,Andjelkovic, M., Van Overmeire, I., Joly, L., Poma, G., Malarvannan, G., Vleminckx, C., Malysheva, S. V., Vanhouche, M., Van Loco, J., Van Nieuwenhuyse, A. and Covaci, A., Journal of Environmental Exposure Assessment, Dec 2024, Vol. 3, no. 4.
https://doi.org/10.20517/jeea.2024.22
Bio-monitoring of endocrine disrupting chemicals in human serum: insights from a study in Central India,
Sharma, P., Pal, N., Singh, S., Ojha, R., Kumawat, M., Shubham, S., Verma, V., Tiwari, R. R., Sarma, D. K. and Kumar, M., International Journal of Environmental Health Research, 2025.
https://doi.org/10.1080/09603123.2025.2502636
A systematic review of pre-analytical factors in urinary EDCs biomonitoring: Toward robust epidemiological studies,
Wu, L. X., Jiang, Y., Xie, S. S., Zhu, B. Q. and Ye, X. Q., Microchemical Journal, Jul 2025, Vol. 214.
https://doi.org/10.1016/j.microc.2025.113968
Analysis of Phthalate Monoesters and Bisphenols in Human Prostate Cancer Tissue and Urine,
Zhang, T. N., Guo, J. Q., Sun, W. Y., Huang, X. Y., Zhang, Z. L., Jin, Y. M., Hu, Z. F., Qiu, S. and Zou, X. L., Journal of Separation Science, Apr 2025, Vol. 48, no. 4.
https://doi.org/10.1002/jssc.70154
Méthodes
The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays,Kos, V. M., Arvidsson, S., Islam, B., Nikiforova, V., Mickols, E., Meyer, A., Svensson, R., Boztepe, U. G., Banti, E., Lundquist, P., Khalidi, H., Gardner, I., Spjuth, O., Cotgreave, I. and Artursson, P., Environmental Toxicology and Pharmacology, Aug 2025, Vol. 117.
https://doi.org/10.1016/j.etap.2025.104750
Testing the Development of a Diet-Based Bisphenol a Score to Facilitate Studies on Child Neurodevelopment: A Pilot Project,
Patti, M. A., Kivumbi, A., Rando, J., Song, A., Croen, L. A., Schmidt, R. J., Volk, H. E. and Lyall, K., Int J Environ Res Public Health, Jul 25 2025, Vol. 22, no. 8.
https://doi.org/10.3390/ijerph22081174
Inter-laboratory validation study of an in vitro glucocorticoid receptor transactivation assay for testing potential endocrine disrupting chemicals,
Rivero-Arze, A., Grimaldi, M., Maillet, G., Gesbert, C., Michelin, E., Garoche, C., Maillot-Maréchal, E., Palluel, O., Sermier, F., Hoffmann, S., Couteau, J., Hubert, P., Grignard, E., Aït-Aïssa, S., Balaguer, P. and Österlund, T., Toxicol In Vitro, Dec 2025, Vol. 109, p. 106109.
https://doi.org/10.1016/j.tiv.2025.106109
[Methodological monitoring of the effects of endocrine disruptors in complex health maintenance],
Sepp, K., Kiss, P. S., László, A., Valkusz, Z., Radács, M., Gálfi, M. and Molnár, Z., Orv Hetil, Aug 3 2025, Vol. 166, no. 31, p. 1209-1216.
https://doi.org/10.1556/650.2025.33353
Applying New Approach Methods for Toxicokinetics for Chemical Risk Assessment,
Wambaugh, J. F., Paul Friedman, K., Beal, M. A., Moffat, I., Hughes, M. F., Nong, A., Dorne, J. C. M., Ashraf, M. W., Barton-Maclaren, T. S., Devito, M., Ferguson, S. S., Judson, R. S., Long, A. S., Paini, A., Sampani, S., Thomas, R. S. and Wetmore, B. A., Chem Res Toxicol, Aug 18 2025, Vol. 38, no. 8, p. 1408-1441.
https://doi.org/10.1021/acs.chemrestox.5c00161
Biomonitoring Xenobiotics in Human Biospecimens: Challenges, Advances, and the Future of Exposome Characterization,
Zhu, X. R., Tang, X. N., Ng, C., Li, L., Lai, Y. J., Miller, G. W., Jiang, C., Barchowsky, A., Buchanich, J. and Gao, P., Reviews of Environmental Contamination and Toxicology, Dec 2025, Vol. 263, no. 1.
https://doi.org/10.1007/s44169-025-00088-2
Agenda, politique, actualité, société et évaluation du caractère PE des substances
ECHA publishes updated PFAS restriction proposal / Timeline for PFAS restriction evaluation announced,ECHA ( aout 2025),
https://echa.europa.eu/hot-topics/perfluoroalkyl-chemicals-pfas#msdynmkt_trackingcontext=4d7029c5-ca2f-4104-bb9f-a0787db50000
Etablissements de santé et perturbateurs endocriniens
(2025). ARS. https://www.auvergne-rhone-alpes.ars.sante.fr/etablissements-de-sante-et-perturbateurs-endocriniens
EU Guidance for transitioning to Fluorine-Free Firefighting Foams,
ECHA (2025),
https://echa.europa.eu/documents/10162/6956102/EU_guidance_for_transitioning_to_fluorine-free_firefighting_foams_en.pdf/24d79e79-a1af-dd0c-0b31-bdc2f78f08fe#msdynmkt_trackingcontext=99e7c4fd-075d-4f8f-9a46-a2b2fa760300
Perturbateurs endocriniens : les esthéticiennes dans la difficulté avec des stocks de vernis interdits,
France Info, 8 septembre 2025.
https://doi.org/https://france3-regions.franceinfo.fr/bourgogne-franche-comte/saone-et-loire/le-creusot/perturbateurs-endocriniens-les-estheticiennes-dans-la-difficulte-avec-des-stocks-de-produits-interdits-3212999.html
Replay Webinaire : Communicating about EDCs & Health: Why words matter,
CHE Collaborative for Health and Environment (juillet 2025),
http://healthandenvironment.org/che-webinars/96990
Webinaire - Perturbateurs endocriniens : les repérer pour prévenir les risques en entreprise -
Rendez-vous le 21 novembre 2025 à 11 heures,
INRS (novembre 2025),
https://www.inrs.fr/footer/agenda/webinaire-perturbateurs-endocriniens-21-11-2025.html
Food-Borne Endocrine-Disruption: An EU Risk Governance Perspective,
El Gemayel, M., European Journal of Risk Regulation, 2025.
https://doi.org/10.1017/err.2025.10017
A review of microplastic pollution and human health risk assessment: current knowledge and future outlook,
Hoang, H. G., Nguyen, N. S. H., Zhang, T., Tran, H. T., Mukherjee, S. and Naidu, R., Frontiers in Environmental Science, Jun 18 2025, Vol. 13.
https://doi.org/10.3389/fenvs.2025.1606332
Assessment of endocrine disruptors in the European Union: Current regulatory framework, use of new approach methodologies (NAMs) and recommendations for improvements,
Holmer, M. L., Holmberg, R. D., Despicht, C., Bouftas, N., Axelstad, M., Beronius, A., Zilliacus, J., Van Duursen, M. and Svingen, T., no. 1096-0295 (Electronic).
19
https://doi.org/10.1016/j.yrtph.2025.105883
Global research on endocrine disruptors as emerging hazards for human health and the environment,
Klingelhöfer, D., Braun, M., Dröge, J., Brüggmann, D. and Groneberg, D. A., Frontiers in Endocrinology, Jun 26 2025, Vol. 16.
https://doi.org/10.3389/fendo.2025.1561711
Next generation risk assessment and new approach methodologies for safe and sustainable by design chemicals and materials: Perspectives and challenges for occupational health,
Leso, V., Nowack, B., Karakoltzidis, A., Nikiforou, F., Karakitsios, S., Sarigiannis, D. and Iavicoli, I., Toxicology, Nov 2025, Vol. 517, p. 154211.
https://doi.org/10.1016/j.tox.2025.154211
Does my patient need testing for PFAS 'forever chemicals'?,
Zuccaro, P., Valvi, D. and Vasiliou, V., Cleve Clin J Med, Aug 1 2025, Vol. 92, no. 8, p. 463-465.
https://doi.org/10.3949/ccjm.92a.24082
Toxicité sur les animaux
The environmental contaminants, tributyltin and bisphenol S, alone or in combination, harm the hypothalamus-pituitary-gonadal axis and uterus,Anselmo, D. D., Azeredo, D. B. C., Röpke, R., Jr., Souza, L. L. D., Lisboa, P. C., Graceli, J. B., Gitirana, L. D., Ferreira, A. C. F., Paiva-Melo, F. D. and Miranda-Alves, L., Molecular and Cellular Endocrinology, Aug 1 2025, Vol. 605.
https://doi.org/10.1016/j.mce.2025.112558
Developmental neurotoxicity of bisphenol F and bisphenol S in animal model systems: A literature review,
Cantua, R. and Mulligan, K., Neurotoxicology, May 2025, Vol. 108, p. 263-280.
https://doi.org/10.1016/j.neuro.2025.04.008
Perinatal bisphenol A exposure impairs gut microbial colonization: Implications for offspring obesity and neurodevelopment,
López-Moreno, A., Torres-Sánchez, A., Suárez, A., Ruiz-Rodríguez, A. and Aguilera, M., Ecotoxicology and Environmental Safety, Jun 15 2025, Vol. 298.
https://doi.org/10.1016/j.ecoenv.2025.118295
In vitro effects of environmentally relevant concentrations of nonylphenol and selected pyrethroid metabolites on a mouse sertoli cell line (TM4),
Matjomane, N. K., Repsold, L., Patrick, S. M., Van Zijl, M. C., Visagie, M. H. and Aneck-Hahn, N. H., Toxicology Mechanisms and Methods, 2025.
https://doi.org/10.1080/15376516.2025.2528100
Exposure to brominated flame retardants during pregnancy and lactation increases the prevalence of breast lesions and cancer-associated pathways in sprague-dawley rats,
Mcdermott, A., Juárez, M., Wade, M. G., Patten, S. A. and Plante, I., Reproductive Toxicology, Aug 2025, Vol. 135.
https://doi.org/10.1016/j.reprotox.2025.108928
Assessing placental transfer and in utero reproductive effects in rats of a short-chained paraffin with in vitro endocrine disrupting properties,
Melchiors, M., Rosenmai, A. K., Cariou, R., Pedersen, M., Christiansen, S. and Svingen, T., Current Research in Toxicology, 2025 2025, Vol. 8.
https://doi.org/10.1016/j.crtox.2025.100237
Effects of carbamazepine-exposure on rat epididymal sperm in parental (F0) and F1 generations,
Nunes, M., De Britto, C. C., Freitas, R. D. D., Oliveira, A. S., Fischer, L. W., Miraglia, S. M. and De Oliva, S. U., Reproductive Toxicology, Sep 2025, Vol. 136.
https://doi.org/10.1016/j.reprotox.2025.108981
Gestational and Lactational Exposure to Perfluorohexanoic Acid Affects Behavior in Adult Male Mice: A Preliminary Study,
Plunk, E. C., Manz, K. E., Gomes, A., Pennell, K. D., Sobolewski, M. E. and Majewska, A. K., European Journal of Neuroscience, Jul 2025, Vol. 62, no. 1.
https://doi.org/10.1111/ejn.70174
Dye intermediates N-phenyl-2-naphthylamine and o-tolidine are novel environmental androgens with reproductive toxicity in male rats,
Shangguan, Z. H., Yang, K. Q., Pan, Q., Hu, H. L. and Wang, P., Reproductive Toxicology, Sep 2025, Vol. 136.
https://doi.org/10.1016/j.reprotox.2025.108955
Bayesian benchmark dose modeling analysis and derivation of points of departure for female reproductive toxicity following exposure to di(2-ethylhexyl) phthalate (DEHP) - effects on reproductive hormones, folliculogenesis and estrous cyclicity,
Silva, A. V., Tarvainen, I., Öberg, M., Laws, M., Hannon, P., Flaws, J. and Damdimopoulou, P., Toxicological Sciences, 2025.
https://doi.org/10.1093/toxsci/kfaf052
In Utero Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Impairs the Ability of Mice to Clear a Pseudomonas aeruginosa Infection in Adulthood,
Stephens, V. R., Bohannon, J. K., Bruner-Tran, K. L., Davis, X. D., Oliver, M. A., Mcbride, M. A., Ameli, S., Rumph, J. T., Gaddy, J. A., Sherwood, E. R. and Osteen, K. G., Microbiology Research, Apr 26 2025, Vol. 16, no. 5.
https://doi.org/10.3390/microbiolres16050091
Pubertal atrazine exposure promotes adipocyte hypertrophy and hepatic steatosis in adult mice on a high-fat diet,
Teleken, J. L., Conte, I. C. M., Schorr, G., Glugoski, L., Bergenthal, L., Alves, J. L., Vicari, V. N., Vicari, M. R., Ribeiro, R. A. and Bonfleur, M. L., Drug and Chemical Toxicology, 2025.
https://doi.org/10.1080/01480545.2025.2534714
Bisphenol A exposure induces polycystic ovarian syndrome phenotype B and reduces fertility in adolescent female rats,
Zhang, W. J., Huang, R. F., Chen, J. H., Ren, L. L., Wang, L., Chen, Q. H. and Zhou, W. D., Reproductive Biomedicine Online, Jul 2025, Vol. 51, no. 1.
https://doi.org/10.1016/j.rbmo.2025.104831
Écrit par Nathalie TOULEMONDE