Bulletin de veille Perturbateurs endocriniens, n°30, mai 2025
Exposition professionnelle
Occupational Exposure to Pesticides Among Farmworkers in Morocco: A Study Framework for Endocrine and Epigenetic Effect Assessment.
Chbihi K, Menouni A, Berni I, Chetouani H, Abou-Said S, Amellah A, et al. Toxics. 2025 Apr 25;13(5).
CO10.1 - Maternal occupational multi-exposure during pregnancy and intrauterine growth: analysis of the French Longitudinal Study of Children - ELFE cohort, using data-driven approaches.
Tartaglia M, Ge C, Pronk A, Costet N, Audignon-Durand S, Houot M, et al. J Epidemiol Popul Health. 2025 2025 May 01;73:203019.
Cadmium Associated Preeclampsia: A Systematic Literature Review of Pregnancy and Birth Outcomes.
Sardar F, Kamsani YS, Ramly F, Mohamed Noor Khan NA, Sardar R, Aminuddin AA. Biol Trace Elem Res. 2025 May;203(5):2505-16.
Polycyclic Aromatic Hydrocarbons (PAHs) in the Environment: Occupational Exposure, Health Risks and Fertility Implications.
Montano L, Baldini GM, Piscopo M, Liguori G, Lombardi R, Ricciardi M, et al. Toxics. 2025 Feb 23;13(3).
Endocrine-disrupting pesticide exposure relevant to reproductive health: a case study from Costa Rica,
Apú, N., Rommes, F., Alvarado-Arias, M., Méndez-Rivera, M. and Lizano-Fallas, V., Environmental Monitoring and Assessment, Apr 2025, Vol. 197, no. 5.
https://doi.org/10.1007/s10661-025-14011-8
Environmental Pollutants, Occupational Exposures, and Liver Disease,
Beier, J. I., Luo, J. Z., Vanderpuye, C. M., Brizendine, P., Muddasani, P., Bolatimi, O., Heinig, S. A., Ekuban, F. A., Siddiqui, H., Ekuban, A., Gripshover, T. C., Wahlang, B., Watson, W. H. and Cave, M. C., Seminars in Liver Disease, Jun 2025, Vol. 45, no. 02, p. 148-166.
https://doi.org/10.1055/a-2540-2861
Investigating the relationship between pesticide exposure, GSTM1 and GSTT1 polymorphisms, and oxidative stress biomarkers in affected farmers,
Hemlata, Rani, M., Kumar, A., Dhiman, S. S. and Et, C., Toxicology and Industrial Health, 2025 2025, Vol. 41, no. 4, p. 220-233, ill., bibliogr., https://doi.org/10.1177/07482337251325578
Managing adherence, exposure, and toxicity in oral anticancer therapies,
Kobayashi, K., Journal of Pharmaceutical Health Care and Sciences, Apr 2025, Vol. 11, no. 1.
https://doi.org/10.1186/s40780-025-00437-2
Pesticide Exposure in Agricultural Workplaces and Resultant Health Effects in Women,
Kumar, S. N., Khan, N. H., Reda, Y., Beigh, H. H., Bastia, B., Vaibhav, K., Jain, A. K. and Raisuddin, S., Birth Defects Research, Apr 2025, Vol. 117, no. 4.
https://doi.org/10.1002/bdr2.2460
Epidémiologie
Foreign Contaminants Target Brain Health,
Agarwal, U., Pannu, A. and Tonk, R. K., Cns & Neurological Disorders-Drug Targets, 2025, Vol. 24, no. 5, p. 353-374.
https://doi.org/10.2174/0118715273338071241213101016
Phthalate Metabolites and Their Relationship with Abdominal and General Obesity: Evidence from the Aragon Workers' Health Study (AWHS). ,
Akritidis, J. a.-O. X., Mérida, D. a.-O., Torrijo-Belanche, C. a.-O., Moreno-Franco, B., Gimeno-Ruiz, S. a.-O., Rey-García, J. a.-O., Morales-Suarez-Varela, M. a.-O. and Guallar-Castillón, P. a.-O., no. 2072-6643 (Electronic).
https://doi.org/10.3390/nu17111869
Neuromotor effects of early-life exposure to a mixture of endocrine disruptors in Belgian preschool children,
Barrea, C., Dufour, P., Catherine, P., Charlier, C., Brevers, F., Parent, A. S. and Rousselle, L., Environmental Health, Mar 2025, Vol. 24, no. 1.
https://doi.org/10.1186/s12940-025-01156-9
Prenatal PFAS exposure associates with DXA assessed markers of adiposity in 7-year-old children from the Odense Child Cohort,
Beck, I. H., Grontved, A., Palm, C. V. B., Batzella, E., Sigvaldsen, A., Dalgard, C., Jensen, R. C., Nielsen, C., Halldorsson, T. I. and Jensen, T. K., Environmental Research, Jun 2025, Vol. 275.
https://doi.org/10.1016/j.envres.2025.121394
Comprehensive Nontargeted Analysis of Drinking Water Supplies to Identify Chemicals Associated with Estrogen Receptor Agonism or Present in Regions of Elevated Breast Cancer Occurrence,
Black, G. P., Anderson, B. N., Wong, L., Alaimo, C. P., He, G. C., Denison, M. S., Bennett, D. H., Tancredi, D., Durbin-Johnson, B., Hammock, B. D., Chowdhary, P., Rubin, R. and Young, T. M., Environmental Science & Technology, Mar 2025, Vol. 59, no. 10, p. 5237-5248.
https://doi.org/10.1021/acs.est.4c12204
Fine particulate matter components and reproductive hormones in female adults: A 15-year longitudinal cohort study,
Chen, S. Y., Guo, C., Ou, C. Q., Zheng, Y. L., Liu, Y. F., Ma, J., Lu, X. C., Huang, B. and Chan, T. C., International Journal of Hygiene and Environmental Health, May 2025, Vol. 266.
https://doi.org/10.1016/j.ijheh.2025.114562
Intergenerational and transgenerational effects of endocrine-disrupting chemicals in the offspring brain development and behavior,
Dias, G. R. M., Giusti, F. C. V., De Novais, C. O., De Oliveira, M. a. L., Paiva, A. G., Kalil-Cutti, B., Mahoney, M. M. and Graceli, J. B., no. 1664-2392 (Print).
Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina,
Doná, F., Lorenz, V., Stegmayer, G., Ricardo, T., D'iorio, S., Ponzo, F., Repetti, M. R., Demonte, L. D., Milesi, M. M. and Varayoud, J., no. 2673-3080 (Electronic).
https://doi.org/https://doi.org/10.3389/ftox.2025.1579952
Examining the Impact of Environmental Non-Persistent Compounds: Phthalates, BPA, and Benzophenone on Endometriosis,
Fuzak, M. K. and Pollack, A. Z., Seminars in Reproductive Medicine, Dec 2024, Vol. 42, no. 04, p. 274-287.
https://doi.org/10.1055/s-0045-1802986
Association between mixed exposure to dioxins and dioxin-like polychlorinated biphenyls and obesity among U.S. adults.,
Gao, Z. X., Zhang, P., Xu, S. Z., He, Y. S., Hu, X., Ge, M., Xu, Y. Q., He, T., Wang, P. a.-O. X. and Pan, H. a.-O., no. 1945-7197 (Electronic).
https://doi.org/https://doi.org/10.1210/clinem/dgae873
Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome,
Gokyer, D., Laws, M. J., Kleinhans, A., Riley, J. K., Flaws, J. A. and Babayev, E., F&S Science, Feb 2025, Vol. 6, no. 1, p. 30-41.
https://doi.org/10.1016/j.xfss.2024.10.009
Unraveling the connection between endocrine-disrupting chemicals and anxiety: An integrative epidemiological and bioinformatic perspective,
Guo, Z., Tan, Y. X., Lin, C. H., Li, H. Y., Xie, Q. Q., Lai, Z. T., Liang, X., Tan, L. and Jing, C. X., Ecotoxicology and Environmental Safety, May 2025, Vol. 296.
https://doi.org/10.1016/j.ecoenv.2025.118188
Fetal exposure to a mixture of endocrine-disrupting chemicals and biomarkers of male fecundity: A population-based cohort study,
Hull, S. D., Hougaard, K. S., Toft, G., Petersen, K. K. U., Flachs, E. M., Lindh, C., Ramlau-Hansen, C. H., Wise, L. A., Wilcox, A., Liew, Z., Bonde, J. P. and Tottenborg, S. S., Andrology, Apr 2025.
https://doi.org/10.1111/andr.70039
Endocrine-disrupting chemicals and clinical outcomes in children with attention-deficit/hyperactivity disorder undergoing methylphenidate treatment: A 12-month follow-up study,
Hwang, J. W., Huang, W. T., Li, C. J., Tsai, C. S., Chou, W. J., Chen, C. C., Lee, S. Y. and Wang, L. J., Environmental Technology & Innovation, May 2025, Vol. 38.
https://doi.org/10.1016/j.eti.2025.104111
Phosphate Flame Retardants and Plasticizers and Their Association with Reproductive and Steroid Hormone Levels among Peripubertal-Aged Children: The Hokkaido Birth Cohort Study,
Ikeda, A., Yamaguchi, T., Bamai, Y. A., Roggeman, M., Ikenaka, Y., Zeng, Y., Yasuda, A., Ketema, R. M., Marsela, M., Gys, C., Den Ouden, F., Itoh, S., Nakamura, A., Kitta, T., Kon, M., Manabe, A., Covaci, A. and Kishi, R., Environmental Science & Technology, Mar 2025, Vol. 59, no. 10, p. 4820-4831.
https://doi.org/10.1021/acs.est.4c11436
The potential health risks of exposure to environmental chemicals - Global implications for future generations,
Kishi, R., Ikeda, A. and Ketema, R. M., Proceedings of the Japan Academy Series B-Physical and Biological Sciences, 2025, Vol. 101, no. 4, p. 197-215.
https://doi.org/10.2183/pjab.101.015
Phthalates may impact key genital measurement in three-year-old children,
L., L., European Society of Endocrinology (ESE) and The European Society for Paediatric Endocrinology (ESPE) (mai 2025),
https://espe-ese-congress2025.org/wp-content/uploads/2025/05/press_release_Lucaccioni-final.pdf
Associations between organophosphate flame retardants metabolites in follicular fluid and reproductive outcomes among women undergoing IVF/ICSI treatment in Southwest China,
Li, X. H., Qiu, J. H., Gan, Z. W., Li, S. W. and Zeng, X., Reproductive Biology and Endocrinology, Apr 2025, Vol. 23, no. 1.
https://doi.org/10.1186/s12958-025-01390-3
Association between endocrine disrupting chemicals exposure and diabetic kidney disease in adults: A national cross-sectional NHANES study,
Li, X. R., Ye, X. A., Xu, L. H. and Chen, H. Y., Ecotoxicology and Environmental Safety, Mar 2025, Vol. 293.
https://doi.org/10.1016/j.ecoenv.2025.118044
Community-based insights into the connection between endocrine-disrupting chemicals and depressive symptoms,
Liu, Y. A., Hsu, H. J., Pan, H. C., Sun, C. Y., Chen, Y. T., Lee, C. C., Su, F. C., Wei, Y. C., Hsu, C. K. and Chen, C. Y., Current Research in Toxicology, 2025, Vol. 8.
https://doi.org/10.1016/j.crtox.2025.100225
Endocrine-disrupting chemicals in human adipose tissue and associations between exposure and obesity,
Lu, Z. H., Li, A. J., Gao, Y., Shi, H. W., Shi, X. L., Li, W. J., Song, J. H. and Song, M. Y., Journal of Environmental Sciences, Sep 2025, Vol. 155, p. 552-561.
https://doi.org/10.1016/j.jes.2024.09.008
ENVIRONMENTAL EXPOSURE TO SELECTED NON-PERSISTENT ENDOCRINE DISRUPTING CHEMICALS AND POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW,
Ozga, M. and Jurewicz, J., International Journal of Occupational Medicine and Environmental Health, 2025, Vol. 38, no. 2, p. 98-121.
https://doi.org/10.13075/ijomeh.1896.02551
Prenatal Concentrations of Perfluoroalkyl Substances and Maternal Beta Cell Function at 7 to 9 Years of Follow-Up,
Palaniyandi, J., Bruin, J. E., Fisher, M., Borghese, M. M., Hoyeck, M. P., Panagiotopoulos, C. and Ashley-Martin, J., Journal of Clinical Endocrinology & Metabolism, Mar 2025.
https://doi.org/10.1210/clinem/dgaf143
Endocrine disruptors as risk factors for idiopathic premature thelarche in girls: A case-control study,
Palmieri, F. I., Gryngarten, M. G., Arcari, A. J., Umido, V. and Freire, A., Archivos Argentinos De Pediatria, Apr 2025.
https://doi.org/10.5546/aap.2024-10501.eng
One year respiratory and neurodevelopmental outcome of premature neonates after exposure to plasticizers in the neonatal intensive care unit - A prospective cohort study,
Panneel, L., Cleys, P., Bamai, Y. A., Dewispelaere, L., Laroche, S., Van Hoorenbeeck, K., Verhulst, S., Covaci, A., Mulder, A. and Jorens, P. G., Environmental Research, Jun 2025, Vol. 274.
https://doi.org/10.1016/j.envres.2025.121266
The Role of Industrial Chemicals and Occupational Hazards in Male Infertility: A Comprehensive Review,
Parvez, K. F. and Hussain, S. S., Metallurgical & Materials Engineering, 2025, Vol. 31, no. 1, p. 52-65.
https://doi.org/https://metall-mater-eng.com/index.php/home/article/view/1207
Endocrine-Disrupting Chemicals and the Effects of Distorted Epigenetics on Preeclampsia: A Systematic Review,
Rani, B. U., Vasantharekha, R., Santosh, W., Swarnalingam, T. and Barathi, S., Cells, Mar 2025, Vol. 14, no. 7.
https://doi.org/10.3390/cells14070493
Association between PFAS exposure and metabolic-related biomarkers in Spanish adolescents,
Rodriguez-Carrillo, A., Vela-Soria, F., Smagulova, F., Fernández, M. F. and Freire, C., Environmental Research, May 2025, Vol. 273.
https://doi.org/10.1016/j.envres.2025.121171
Hidden link between endocrine-disrupting chemicals and pediatric obesity,
Shin, M. W. and Kim, S. H., Clinical and Experimental Pediatrics, Mar 2025, Vol. 68, no. 3, p. 199-222.
https://doi.org/10.3345/cep.2024.00556
Fetal exposure to phthalates and body mass index from infancy to adolescence. The Generation R study,
Sol, C. M., Delgado, G., Kannan, K., Jaddoe, V. W. V., Trasande, L. and Santos, S., Environmental Research, Jun 2025, Vol. 274.
https://doi.org/10.1016/j.envres.2025.121253
Adverse Effects of Pesticides on the Ovary: Evidence from Epidemiological and Toxicological Studies,
Wang, L. P., Ma, X. C. and Liu, J., Environment & Health, Mar 2025.
https://doi.org/10.1021/envhealth.4c00243
Association between ethylene oxide exposure and serum sex hormone levels measured in a reference sample of the US general population,
Wu, W. H., Wu, J. N., Hou, Z. B., Yan, Q., Qin, K. X., Zhao, Y., Zhang, H., Zhu, Y. K., He, J. H. and Li, J., Frontiers in Endocrinology, Apr 2025, Vol. 16.
https://doi.org/10.3389/fendo.2025.1533516
Exploring the relationships between prenatal phthalate exposure and neonatal thyroid function: A prospective cohort study,
Xiong, Z. Y., Mahai, G., Wang, A. Z., Li, F. S., Qian, X., Huang, Y. Z., Li, Y. Y., Xia, W. and Xu, S. Q., Journal of Hazardous Materials, Jul 2025, Vol. 492.
https://doi.org/10.1016/j.jhazmat.2025.138132
Microbial Disturbances Caused by Pesticide Exposure and Their Predictive Implications for Gestational Diabetes Mellitus,
Yang, X., Zhang, Y. Q., Xu, Y. F., Xu, Y. D., Zhang, M. Z., Guan, Q. Q., Hu, W. Y., Tun, H. M. and Xia, Y. K., Environmental Science & Technology, May 2025, Vol. 59, no. 19, p. 9449-9460.
https://doi.org/10.1021/acs.est.5c01076
Associations between urinary phthalate metabolites and reproductive, adrenal, and gonadotropic hormones in peripubertal children: the Hokkaido study,
Yasuda, A., Bamai, Y. A., Yamaguchi, T., Ketema, R. M., Zeng, Y., Marsela, M., Ikenaka, Y., Nakamura, A., Kitta, T., Kon, M., Manabe, A., Kishi, R., Kojima, H. and Ikeda, A., Environmental Research, Jul 2025, Vol. 276.
https://doi.org/10.1016/j.envres.2025.121535
Association Between Endocrine-Disrupting Chemicals Exposure and Attention-Deficit/Hyperactivity Disorder Symptoms in Children With Attention-Deficit/ Hyperactivity Disorder,
Yeo, K. E., Lim, S., Kim, A., Lim, Y. B., Lee, C. R., Kim, J. I. and Kim, B. N., Journal of the Korean Academy of Child and Adolescent Psychiatry, Jan 2025, Vol. 36, no. 1, p. 18-25.
https://doi.org/10.5765/jkacap.240035
Association between per- and polyfluoroalkyl substance exposures and thyroid homeostasis parameters. ,
Yu, X., Liu, Y., Wang, M., Jia, P., Yang, S., Sun, F., Jin, Y., Wang, X., Guo, Z., Zhao G Auid- Orcid: --- Fau - Gao, B. and Gao, B. a.-O. X., The Journal of Clinical Endocrinology & Metabolism, no. 1945-7197 (Electronic).
https://doi.org/https://doi.org/10.1210/clinem/dgae798
First evidence in the association of phenolic endocrine-disrupting chemicals with secondary non-alcoholic fatty liver disease: A case-control study in South China,
Zhang, H. L., Feng, S., Song, S. M., Zhao, Q., Gao, Y. X. and Zhang, T., Environmental Pollution, May 2025, Vol. 373.
https://doi.org/10.1016/j.envpol.2025.126086
Association between exposure to perfluoroalkyl substances (PFASs) and risk of hyperemesis gravidarum,
Zhang, L., Ma, X. X., Su, T., Wang, Y., Hai, M. M., Qi, F. F., Ma, L., Zhang, S. M. and Lin, J., Environmental Pollution, May 2025, Vol. 373.
https://doi.org/10.1016/j.envpol.2025.126103
Association between urinary polycyclic aromatic hydrocarbons and childhood obesity index: a cross-sectional study in China,
Zhang, Q., Wu, D., Luo, J., Chen, Z. X., Wang, Y. J., Tian, Y., He, Z. W. and Liu, Q., Human and Ecological Risk Assessment, Apr 2025, Vol. 31, no. 3-4, p. 587-604.
https://doi.org/10.1080/10807039.2025.2470759
Associations of endocrine-disrupting chemicals mixtures with serum lipid and glucose metabolism among overweight/obese and normal-weight children: A panel study,
Zhang, Y. Y., Zhang, B., Yang, H. H., Liu, M., Wang, J., Zhao, L., Guo, W. T., Li, M., Lai, X. F., Yang, L. L., Meng, X., Wang, C. J., Zhang, Z. H. and Zhang, X. M., Ecotoxicology and Environmental Safety, Apr 2025, Vol. 294.
https://doi.org/10.1016/j.ecoenv.2025.118077
Associations between in utero exposure of per- and polyfluoroalkyl substances (PFAS) mixture and anthropometry measures at birth,
Zhao, N., Zhang, X. Z., Li, Y. H., Zhang, H. Y., Yang, E., Ding, L. and Liu, Y., Environmental Pollution, May 2025, Vol. 373.
https://doi.org/10.1016/j.envpol.2025.126093
Urinary concentrations of phthalate metabolites and the survival of high-grade serous ovarian cancer with advanced stage,
Zheng, W. R., Li, Y. Z., Xu, J., Liu, K. X., Liu, F. H., Xing, W. Y., Liu, J. X., Wu, L., Li, X. Y., Huang, D. H., Gong, T. T. and Wu, Q. J., Environmental Pollution, Apr 2025, Vol. 370.
https://doi.org/10.1016/j.envpol.2025.125895
Association and binding interaction between per- and polyfluoroalkyl substances and maternal thyroid hormones: A case study based on a prospective birth cohort in Wuxi, China,
Zhou, Y. H., Xu, L. L., Yan, Y., Li, Y., Wang, S. A., Ding, X. L., Zhu, P. F., Jiao, J. D., Zhang, L., Ma, J. Q. and Chen, L. M., Environmental Research, Jun 2025, Vol. 275.
https://doi.org/10.1016/j.envres.2025.121439
Toxicité sur l’homme
In Vitro Exposure to the Endocrine-Disrupting Chemical Climbazole Impairs Human Sperm Motility, Hormonal Signalling, and Mitochondrial Activity,
Annunzi, E., Luongo, F. P., Girolamo, F., Ponchia, R., Passaponti, S., Piomboni, P. and Luddi, A., Cells, Mar 2025, Vol. 14, no. 6.
https://doi.org/10.3390/cells14060427
Bisphenol A and DDT disrupt adipocyte function in the mammary gland: implications for breast cancer risk and progression,
Bernhardt, S. M. and House, C. D., Frontiers in Oncology, Feb 2025, Vol. 15.
https://doi.org/10.3389/fonc.2025.1490898
Insecticides and testicular health: mechanisms of injury and protective natural products,
Darwish, S. F., Moustafa, Y. M., Mageed, S. S. A., Hassan, G. S., Mangoura, S. A., Aly, S. H., Mansour, M. A., Raouf, A. A., Sallam, A. M., Fawzi, S. F., Atta, A. M., Elazazy, O., El-Dakroury, W. A., El-Demerdash, A. A., Esmat, E. M., Elrebehy, M. A. and Doghish, A. S., Naunyn-Schmiedebergs Archives of Pharmacology, Mar 2025.
https://doi.org/10.1007/s00210-025-04016-y
Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network,
Dierichs, N., Piersma, A. H., Peeters, R. P., Visser, W. E., Meima, M. E. and Hessel, E. V. S., Critical Reviews in Toxicology, Mar 2025, Vol. 55, no. 3, p. 304-320.
https://doi.org/10.1080/10408444.2025.2461076
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts,
Gaillard, L., Barouki, R., Blanc, E., Coumoul, X. and Andreau, K., Trends in Endocrinology and Metabolism, Mar 2025, Vol. 36, no. 3, p. 249-261.
https://doi.org/10.1016/j.tem.2024.07.021
Impact of Persistent Endocrine-Disrupting Chemicals on Human Nuclear Receptors: Insights from In Silico and Experimental Characterization,
Ganesh, H., Moran, J., Roy, S., Mathew, J., Ackah-Blay, J., Costello, E., Shan, P. and Dakshanamurthy, S., International Journal of Molecular Sciences, Mar 2025, Vol. 26, no. 7.
https://doi.org/10.3390/ijms26072879
The Ovary as a Target Organ for New Generation Bisphenols Toxicity,
Glód, P., Smoleniec, J., Marynowicz, W., Gogola-Mruk, J. and Ptak, A., Toxics, Feb 2025, Vol. 13, no. 3.
https://doi.org/10.3390/toxics13030164
Phthalates and Non-Phthalate Plasticizers and Thyroid Dysfunction: Current Evidence and Novel Strategies to Reduce Their Spread in Food Industry and Environment,
Gorini, F., Tonacci, A., Sanmartin, C. and Venturi, F., Toxics, Mar 2025, Vol. 13, no. 3.
https://doi.org/10.3390/toxics13030222
Identification of endocrine disrupting chemicals targeting NTD-related hub genes during pregnancy via in silico analysis,
Guo, J. J., Yu, H., Guo, Y. J., Liu, J. M., Chen, Y. Z. and Li, Z. Z., Reproductive Toxicology, May 2025, Vol. 134.
https://doi.org/10.1016/j.reprotox.2025.108904
Prioritizing endocrine-disrupting chemicals targeting systemic lupus erythematosus genes via Mendelian randomization and colocalization analyses,
Hong, Y. G., Shu, W. Y., Jiang, X. Y., Wang, Y., Chen, R. J., Yang, Q. R., Wang, D. Q., Shao, C. Y., Gao, S. and Hua, C. Y., Ecotoxicology and Environmental Safety, Apr 2025, Vol. 295.
https://doi.org/10.1016/j.ecoenv.2025.118126
Impact of endocrine disruptors in cosmetics on reproductive function in males and females,
Lasaneya, A., Saikia, Q., Dutta, S. and Kalita, J. C., Journal of Environmental Science and Health Part C-Toxicology and Carcinogenesis, Apr 2025, Vol. 43, no. 2, p. 184-207.
https://doi.org/10.1080/26896583.2025.2498831
Plastic chemicals disrupt molecular circadian rhythms via adenosine 1 receptor in vitro,
Mcpartland, M., Ashcroft, F. and Wagner, M., Environment International, Apr 2025, Vol. 198.
https://doi.org/10.1016/j.envint.2025.109422
Parabens exposure and its impact on diabesity: A review,
Ramalho, A., Vale, A., Carvalho, F., Fernandes, E. and Freitas, M., Toxicology, Aug 2025, Vol. 515.
https://doi.org/10.1016/j.tox.2025.154125
Mechanisms of toxicity caused by bisphenol analogs in human in vitro cell models,
Rifa, R. A., Rojo, M. G. and Lavado, R., Chemico-Biological Interactions, May 2025, Vol. 412.
https://doi.org/10.1016/j.cbi.2025.111475
Endocrine disruption potential of dust in children's indoor environments: Associations with multiple chemicals from various compound classes across exposure matrices used for health risk assessment,
Sjöström, Y., Holmes, B., Ricklund, N., Struwe, N., Hagström, K., Hagberg, J. and Larsson, M., Environmental Research, Aug 2025, Vol. 278.
https://doi.org/10.1016/j.envres.2025.121614
Re-Evaluating the Use of Glyphosate-based Herbicides: Implications on Fertility,
Stone, A. M., Camp, O. G., Biernat, M. M., Bai, D., Awonuga, A. O. and Abu-Soud, H. M., Reproductive Sciences, Apr 2025, Vol. 32, no. 4, p. 950-964.
https://doi.org/10.1007/s43032-025-01834-6
Bisphenol A and its replacement chemicals as endocrine disruptors and obesogens,
Tang, Y. Q., Qin, G. Y., Qian, N. N., Zeng, X. Y., Li, R. and Lai, K. P., Environmental Chemistry and Ecotoxicology, 2025, Vol. 7, p. 696-705.
https://doi.org/10.1016/j.enceco.2025.04.001
Lifestyle and Environmental Factors Affecting Male Fertility, Individual Predisposition, Prevention, and Intervention,
Tesarik, J., International Journal of Molecular Sciences, Mar 2025, Vol. 26, no. 6.
https://doi.org/10.3390/ijms26062797
Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omics. ,
Zhao, L., Shi, M., Winuthayanon, S., Maclean Ii, J. A., Law, N. C. and Hayashi, K. a.-O. X., no. 1552-9924 (Electronic).
https://doi.org/https://doi.org/10.1289/EHP16981
Méthodes
Mise à jour de l'essai n° 421 : Essai de dépistage de la toxicité pour la reproduction et le développement. Lignes directrices de l'OCDE pour les essais de produits chimiques, Section 4,
OCDE (25 juin 2025),
https://doi.org/10.1787/9789264264397-fr
Mise à jour de l'essai n° 422 : Étude combinée de toxicité à doses répétées et de dépistage de la toxicité pour la reproduction et le développement. Lignes directrices de l'OCDE pour les essais de produits chimiques, Section 4,
OCDE (25 juin 2025),
https://doi.org/10.1787/9789264264410-fr
Bioinformatics analysis to identify environmental endocrine chemicals that target endometriosis genes,
Du, K. L., Xiong, H. W., Zhang, X. C., Luo, R. H. and Zhou, B. X., Ecotoxicology and Environmental Safety, Apr 2025, Vol. 295.
https://doi.org/10.1016/j.ecoenv.2025.118136
Preparation of novel cationic porous polymers for effective pre-concentration and sensitive detection of endocrine disruptors in water and fish,
Fan, C. C., Dong, Y. L., Li, Z., Wang, Q. Q., Wang, Z., Wu, Q. H. and Wang, C., Analytica Chimica Acta, Jun 2025, Vol. 1353.
https://doi.org/10.1016/j.aca.2025.343956
Caenorhabditis elegans as a Model to Assess the Potential Risk to Human Health Associated with the Use of Bisphenol A and Its Substitutes,
Kaiglová, A., Bardyová, Z., Hockicková, P., Zvolenská, A., Melnikov, K. and Kucharíková, S., International Journal of Molecular Sciences, Mar 2025, Vol. 26, no. 5.
https://doi.org/10.3390/ijms26052013
Concentrations of arsenic (As), cadmium (Cd) and lead (Pb) in blood, hair and semen of stallions in Finland,
Oztas, T., Akar, M., Virkanen, J., Beier, C., Goericke-Pesch, S., Peltoniemi, O., Kareskoski, M. and Björkman, S., Journal of Trace Elements in Medicine and Biology, Jun 2025, Vol. 89.
https://doi.org/10.1016/j.jtemb.2025.127633
Development of Methods for the Early Detection of Chemical Hazard and the Prevention of Pre-disease, Focusing on Environment, Food, and Health,
Sone, H., Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 2025, Vol. 145, no. 3, p. 201-221. https://pubmed.ncbi.nlm.nih.gov/40024733/
Using transcriptomics data and Adverse Outcome Pathway networks to explore endocrine disrupting properties of Cadmium and PCB-126,
Wiklund, L., Wincent, E. and Beronius, A., Environment International, Mar 2025, Vol. 197.
https://doi.org/10.1016/j.envint.2025.109352
Magnetic cationic covalent organic framework for efficient enrichment and detection of phenolic endocrine disruptors in foodstuffs,
Xu, J. Q., Li, W. R., Sun, M., Li, Q. Y., Jiang, F., Wu, Y. N. and Li, G. L., Journal of Chromatography A, May 2025, Vol. 1748.
https://doi.org/10.1016/j.chroma.2025.465827
Unraveling ER dimerization dynamics in endocrine disruption based on a BRET-focused approach,
Yum, S., Lee, H. K., Kwon, Y. K., Lee, G. Y., Lee, H. Y., Youn, H. and Youn, B., Animal Cells and Systems, Dec 2025, Vol. 29, no. 1, p. 282-295.
https://doi.org/10.1080/19768354.2025.2481984
A fluorescence biosensor with a dual-function DNA probe targeting the activated estrogen receptor for estrogenic activity evaluation,
Zhang, Q., Li, Y. W., Li, J. L., Ma, J. T., Li, M. J. and Guo, L. H., Environmental Research, May 2025, Vol. 273.
https://doi.org/10.1016/j.envres.2025.121163
Simultaneous determination of multiple endocrine disrupting chemicals in human amniotic fluid samples by solid phase extraction coupled with liquid chromatography tandem mass spectrometry (LC-MS/MS),
Zhao, L., Lin, Z., Ju, D., Ni, J. Y., Ma, Y. X., Chen, B., Li, X. Z., Sun, C. C., Zheng, J. Q., Zhang, H. P., Hou, S. K., Li, P. H., Song, S. J. and Guo, L. Q., Talanta, Oct 2025, Vol. 293.
https://doi.org/10.1016/j.talanta.2025.128088
Agenda
Journées d'étude : Travail et risques pour la reproduction,
ISTNF Santé Travail (13 et 14 novembre 2025 2025),
https://istnf.fr/actu-216/travail-et-risques-pour-la-reproduction
Le 21ème colloque scientifique de l'ADEREST aura lieu les 27 & 28 novembre 2025 à Besançon ADEREST (2025),
https://www.aderest.org/colloque-1/le-colloque
Safer Chemicals Podcast - PFAS, Chromium VI and worker safety: June committee updates,
ECHA (13 juin 2025),
ENDO 2025. The Signature Annual Meeting in Endocrinology,
Endocrine Society (12-15 juillet 2025),
https://www.endocrine.org/meetings-and-events/endo-2025
Webinar. Communicating about EDCs & Health: Why words matter, 8 juillet 2025.
https://doi.org/https://www.healthandenvironment.org/che-webinars/96990
Compte rendu du Séminaire scientifique « PRÉVENIR » : Reprotoxiques, environnement et travail. 9e Journée de l’Institut Santé-Travail Paris-Est (IST-PE). Créteil, 28 novembre 2024,
Djebien, K., IC RST - Suivi pour vous, Références en santé au travail, 2025 2025, no. 181, p. 105-111, 4.
https://www.inrs.fr/media.html?refINRS=TD%20326
Actualités
Analyse des résultats de l’expertise collective de l’Inserm sur les effets des pesticides sur la santé.
ANSES (24 avril 2025),
https://www.anses.fr/fr/content/analyse-des-resultats-de-lexpertise-collective-inserm
Comment les PFAS menacent aussi la santé des travailleurs,
Actu Environnement (24 juin 2025),
https://www.actu-environnement.com/ae/news/pfas-sante-securite-travail-prevention-inrs-46395.php4
Common phthalate plasticizers pose health risks, EPA finds,
Chemical and engineering news, 13 juin 2025.
Easy Targets: How Endocrine-Disrupting Chemicals Affect Reproductive Endocrinology,
Endocrine News, juin 2025.
Éviter les isoflavones dans les menus des restaurations collectives.
ANSES (24 mars 2025),
https://www.anses.fr/fr/content/eviter-les-isoflavones-dans-les-menus-des-restaurations-collectives
Exposure to ‘Forever Chemicals’ May Affect Thyroid Health,
Endocrine news, avril 2025.
https://endocrinenews.endocrine.org/exposure-to-forever-chemicals-may-affect-thyroid-health/
Kiabi rappelle des sacs pour enfants à cause de la présence d’un perturbateur endocrinien,
Ouest France, 13 juin 2025.
Mind Bending: How Endocrine-Disrupting Chemicals Could Affect Brain Development,
Endocrine News, avril 2025.
New research probes how PFAS-contaminated dust threatens Maine farmworkers,
Environmental Health News, 19 juin 2025.
https://www.ehn.org/new-research-probes-how-pfas-contaminated-dust-threatens-maine-farmworkers
Perturbateurs endocriniens : un escape game pour sensibiliser aux risques sanitaires proposé par la ville de Lyon (69),
ARS Auvergne Rhône Alpes (mai 2025),
PFAS : Une contamination inquiétante de l’alimentation européenne révélée par une nouvelle enquête de Générations Futures,
Générations Futures (juin 2025),
https://www.generations-futures.fr/actualites/pfas-alimentation/
Retrait des produits à base de flufenacet, un pesticides PFAS perturbateur endocrinien et contaminant des eaux souterraines,
Générations Futures (juin 2025),
https://www.generations-futures.fr/actualites/flufenacet-genevard/
Sécurité des jouets : l’UE renforce enfin sa réglementation contre les substances toxiques,
Générations futures (avril 2025),
https://www.generations-futures.fr/actualites/jouets-pfas/
Silent Disruptors: How Environmental Chemicals Threaten Thyroid Health and Development,
Endocrine News, avril 2025.
The story of a Swedish town that suffers the world's worst PFAS contamination,
Envrionmental Health News (24 juin 2025),
Research Progress in Current and Emerging Issues of PFASs' Global Impact: Long-Term Health Effects and Governance of Food Systems,
Lee, J. C., Smaoui, S., Duffill, J., Marandi, B. and Varzakas, T., Foods, Mar 2025, Vol. 14, no. 6.
https://doi.org/10.3390/foods14060958
Bisphenols. New environmental, pathophysiological and social perspectives
Moreno-Gomez-Toledano, R. Londres (Royaume-Uni), IntechOpen. Livre de 175 pages. Avril 2025
https://www.intechopen.com/books/12651
Identification et substitution des perturbateurs endocriniens
Welcome to the PFAS Guide,
4 new pesticides ignite debate over PFAS definition,
Chemical and engineering news, 24 juin 2025.
https://cen.acs.org/environment/pesticides/4-new-pesticides-ignite-debate/103/web/2025/06
Bulletin d'information n°24 - Substitution des substances chimiques,
INERIS (mars 2025),
https://substitution.ineris.fr/sites/substitution-portail/files/newsletter/newsletter24_fr.pdf
Community Rolling Action Plan (CoRAP) update covering the years 2025, 2026 and 2027,
ECHA (25 mars 2025),
Endocrine Disruptor Lists. List updates,
EDLists (juin 2025),
https://edlists.org/list-updates
Occupational exposure limit for Bisphenol A (BPA),
ECHA (18 juin 2025),
Outil Repérage des perturbateurs endocriniens en entreprise. Outil d'aide à l'évaluation du risque chimique.,
Institut national de recherche et de sécurité (INRS) (avril 2025),
https://www.inrs.fr/media.html?refINRS=outil16
Pepper 2025 : Appel à méthodes d’essai pour la perturbation endocrinienne (20 juin 2025),
https://ed-pepper.eu/call-for-methods-2025/
Mechanism-Driven Design of Isothiazolinone Alternatives,
Hu, C. Y., Tang, L. Z., Sun, B. L., Wang, J. L., Zhou, B. S. and Chen, L. G., Environmental Science & Technology, Mar 2025, Vol. 59, no. 14, p. 6983-6992.
https://doi.org/10.1021/acs.est.4c12683
A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health,
Mhaouty-Kodja, S., Zalko, D., Tait, S., Testai, E. and Et, C., Critical Reviews in Toxicology, 2024, Vol. 54, no. 10, p. 696-753, ill., bibliogr.
https://doi.org/10.1080/10408444.2024.2388712
Evaluation de l’exposition et prévention
Development and validation of a survey on reproductive health behaviors to reduce exposure to endocrine-disrupting chemicals in Koreans,
Kim, H. J., Kim, S. H., Choi, S. Y. and Shin, G., Frontiers in Reproductive Health, Mar 2025, Vol. 7.
https://doi.org/10.3389/frph.2025.1519896
Filling gaps in population estimates of phthalate exposure globally: A systematic review and meta-analysis of international biomonitoring data,
Acevedo, J. M., Kahn, L. G., Pierce, K. A., Albergamo, V., Carrasco, A., Manuel, R. S. J., Rosenberg, M. S. and Trasande, L., International Journal of Hygiene and Environmental Health, Apr 2025, Vol. 265.
https://doi.org/10.1016/j.ijheh.2025.114539
Suspect screening of bisphenol A (BPA) structural analogues and functional alternatives in human milk from Canada and South Africa. LID - [doi],
Chi, Z. H., Liu, L., Zheng, J., Tian, L., Chevrier, J., Bornman, R., Obida, M., Goodyer, C. G., Hales, B. F. and Bayen, S. a.-O., no. 1559-064X (Electronic).
https://doi.org/10.1038/s41370-025-00782-2
Release of Bisphenol A from Dental Materials: Risks and Future Perspectives,
Tichy, A. a.-O., Srolerova, T. a.-O. and Schwendicke, F. a.-O., no. 1544-0591 (Electronic).
https://doi.org/10.1177/002203452513377
Are Sleeping Children Exposed to Plasticizers, Flame Retardants, and UV-Filters from Their Mattresses?,
Vaezafshar, S., Wolk, S., Simpson, K., Akhbarizadeh, R., Blum, A., Jantunen, L. M. and Diamond, M. L., Environmental Science & Technology, Apr 2025, Vol. 59, no. 16, p. 7909-7918.
https://doi.org/10.1021/acs.est.5c03560
Toxicité sur les animaux
Tetramethyl bisphenol F exposure induces human ovarian granulosa cell senescence and mouse ovarian damage by regulating ESRRB signalling,
Fan, H. Y., Li, C. M., Lv, Y. F., Qi, T. Y., Huang, Y. Z., Ma, L. J., Lan, Y. B., Chen, P. Q., Lou, Z. and Zhou, J. H., Ecotoxicology and Environmental Safety, Mar 2025, Vol. 292.
https://doi.org/10.1016/j.ecoenv.2025.117940
Atrazine's effects on mammalian physiology,
Holliman, A. G., Mackay, L., Biancardi, V. C., Tao, Y. X. and Foradori, C. D., Journal of Toxicology and Environmental Health-Part B-Critical Reviews, Mar 2025.
https://doi.org/10.1080/10937404.2025.2468212
Propylparaben negatively impacts IN VITRO preimplantation mouse embryo development,
Lai, N. Z. E., Bashir, S. T., Ziv-Gal, A., Sivagaru, M. and Nowak, R. A., Reproductive Toxicology, Apr 2025, Vol. 133.
https://doi.org/10.1016/j.reprotox.2025.108876
Effects of Chemical Speciation on Chronic Thyroid Toxicity of Representative Perfluoroalkyl Acids,
Li, J., Wang, Q., Hu, C. Y., Sun, B. L., Yang, Z. X., Zhou, B. S., Leung, K. M. Y. and Chen, L. G., Environmental Science & Technology, Mar 2025, Vol. 59, no. 14, p. 6959-6970.
https://doi.org/10.1021/acs.est.4c10997
Maternal di(2-ethylhexyl) phthalate exposure increases the risk of congenital heart disease in mice offspring,
Shi, H. Q., Zhang, Z. H., Shen, A. N., Ding, T., Zhao, R., Shi, Y., Zhao, J. Y., Cai, K. and Wang, F., Pediatric Research, Mar 2025.
https://doi.org/10.1038/s41390-025-03997-z
Impact of the environmental endocrine disruptor 4-octylphenol on reproductive function in pubertal male mice,
Zhao, Z. J., Chi, J. Y., Zhang, F. F., Song, Y. L., Xv, W. D., Li, Y. and Shi, H., Environmental Research, Jul 2025, Vol. 276.
https://doi.org/10.1016/j.envres.2025.121530
Developmental programming: mechanisms of early exposure to real-life chemicals in biosolids on offspring ovarian dynamics†,
Zhou, Y. R., Halloran, K. M., Bellingham, M., Lea, R. G., Evans, N. P., Sinclair, K. D., Smith, P. and Padmanabhan, V., Biology of Reproduction, Jun 2025, Vol. 112, no. 6, p. 1229-1242.
https://doi.org/10.1093/biolre/ioaf053
Écrit par Nathalie TOULEMONDE